醋酸奥曲肽在急性重症胰腺炎中的疗效和安全性观察(1)
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[摘要] 目的 探讨醋酸奥曲肽在急性重症胰腺炎中的疗效和安全性。 方法 选取2009年7月～2011年12月于本院进行治疗的52例急性重症胰腺炎患者为研究对象，将其采用随机数字表法分为对照组(常规治疗干预组)和观察组(加用醋酸奥曲肽组)每组各26例，然后将两组患者的治疗总有效率、观察指标改善时间、住院时间及不良反应发生率进行比较。 结果 观察组的总有效率高于对照组，观察指标改善时间及住院时间均短于对照组，不良反应发生率低于对照组，差异有统计学意义(P均 < 0.05)。 结论 醋酸奥曲肽在急性重症胰腺炎中的疗效和安全性均值得肯定，故其在本病中有较高的应用价值。
[关键词] 醋酸奥曲肽；急性重症胰腺炎；疗效；安全性
[中图分类号] R657.5 [文献标识码] A [文章编号] 1674—4721(2012)09(c)—0062—02
Observation on the effect and safety of octreotide acetate in patients with severe acute pancreatitis
WU Zhong
Department of Gastroenterology， Xingang Central Hospital of Xinyu City in Jiangxi Province， Xinyu 338001， China
[Abstract] Objective To study the effect and safety of octreotide acetate in patients with severe acute pancreatitis. Methods Fifty—two patients with severe acute pancreatitis in our hospital from July 2009 to December 2011 were selected as research object， and they were divided into control group (routine treatment group) and observation group (octreotide acetate group) with 26 cases in each group according to random number table， then the total effective rate， improvement times of observation indexes， hospitalization time and incidence of adverse reactions of two groups were compared. Results The total effective rate of observation group was higher than that of control group， improvement times of observation indexes and hospitalization time were shorter than those of control group， incidence of adverse reactions was lower than that of control group， there were all significant differences (P < 0.05). Conclusion The effect and safety of octreotide acetate in patients with severe acute pancreatitis is better， and the application value for the disease is higher ......
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