多种药物联合治疗糖尿病周围神经病变的观察(2)
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本研究结果表明,糖尿病周围神经病变患者加用甲钴胺、胰激肽原酶肠溶片治疗后,其临床症状虽有不同程度改善,但总的效果不是特别令人满意,但加用α-硫辛酸和甲钴胺联合治疗后,疗效明显优于甲钴胺、胰激肽原酶肠溶片治疗的对照组,明显加快神经传导速度。因此,选用α-硫辛酸、甲钴胺联合治疗糖尿病周围神经病变改善临床症状,减轻患者痛苦,为降低糖尿病足发生、减轻患者的经济负担提供了较好的治疗方案,值得推广。
[参考文献]
[1] Wild S,Roglic G,Green A,et al. Global prevalence of diabetes:estimates for the year 2000 and projections for 2030[J]. Diabetes Care,2004,27:1047-1053.
[2] Zhang Dongming,Wang Chongxian,Zhang Suhe. Peripheral neuropathy in type 2 diabetes mellitus and relationship between C peptide[J]. Journal of Practical Nervous Diseases in China,2011,14(3):13.
[3] Li Shiming. Diagnosis and treatment of complications associated with diabetes foot[M]. Beijing:People's Publishing House,2002:274-275.
[4] Cameron NE,Eaton SE,Cotter MA,et al. Va sanlar factors and me tubolic interactions in the pathogenesis of diabetic neuropathy[J]. Diabetolgia,2001,44(11):1973-1988.
[5] Mr LAU Kong-wah,Deng Guoqiang,Liu Zhiwen,et al. Effect of Losartan combined with methycobal in treatment of diabetic peripheral neuropathy:a clinical study[J]. Chinese Journal of Practical Internal Medicine,2011,23(6):357-358.
[6] Chinese Medical Association diabetes branch. Chinese type 2 Diabetes Prevention Guide (2007 Edition)[J]. Chinese Journal of Medicine,2008,88(18):1227-1245.
(收稿日期:2012-11-22 本文编辑:郭静娟)
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