大便隐血与大肠疾病关系的研究(2)
综上所述,早期发现、早期诊断、早期治疗是治疗大肠癌的关键,大规模的随机对照试验显示,FOBT能有效降低16%左右的大肠癌相关病死率,且价格便宜,检测方法便捷[13],因而对于基层医院,FOBT对于大肠癌及癌前病变的筛选来说是一项既简便又实用的大肠癌筛查方法,值得广泛推广应用。
[参考文献]
[1] Jemal A,Siegal R,Ward E,et al.Cancer statistics,2008[J].CA Cancer J Clin,2008,58(2):71-96.
[2] 王继恒,李世荣.我国结直肠癌筛查和早期诊断十年回顾:1994-2005[J].胃肠病学,2006,11(4):245-250.
[3] Gumaste VV.CT colonograghy can be an adjunct to optical colonoscopy in CRC screening[J].Dig Dis Sci,2009,54(2):212-217.
[4] Luo D,Cambon AC,Wu D,et al.Evaluating the long-term effect of FOBT in colorectal cancer screening[J].Cancer Epidemiol,2012,36(1):e54-e60.
[5] 刘国伟.孔祥毓.大肠癌筛查研究[J].医学综述,2008,14(21):32-49.
[6] 王磊,韩树堂.早期大肠癌及癌前病变中西医治疗概况[J].现代中西医结合杂志,2013,22(19):114-116.
[7] 姜泊,龚伟.如何提高早期大肠癌及癌前病变内镜诊断率[J].广东医学,2011,32(1):1-5.
[8] Labianca R,Beretta GD,Kildani B,et al.Colon cancer[J].Crit Rev Oncol Hematol,2010,74(2):106-133.
[9] Mandel JS,Church TR,Bond JH,et al.The effect of fecal occult-blood screening on the incidence of colorectal cancer[J].N Engl J Med,2000,343(22):1603-1607.
[10] Allison JE,Sakoda LC,Levin TR,et al.Screening for colorectal neoplasms with new fecal occult blood tests:update on performance characteristics[J].J Natl Cancer Inst,2007,99(19):1462-1470.
[11] Oort FA,Terhaar Sive Droste JS,Van Der Hulst RW,et al.Colonoscopy-controlled intra-individual comparisons to screen relevant neoplasia:faecal immunochemical test vs. guaiac-based faecal occult blood test[J].Aliment Pharmacol Ther,2010,31(3):432-439.
[12] Parra-Blanco A,Gimeno-García AZ,Quintero E,et al.Diagnostic accuracy of immunochemical versus guaiac faecal occult blood tests for colorectal cancer screening[J].J Gastroenterol,2010,45(7):703-712.
[13] 庄璐,李兆申,蔡全才.犬肠癌筛查方法研究新进展[J].胃肠病学和肝病学杂志,2014,23(1):1-4.
(收稿日期:2014-08-28 本文编辑:许俊琴) (黄珏 田相龙 宋冬霞)
[参考文献]
[1] Jemal A,Siegal R,Ward E,et al.Cancer statistics,2008[J].CA Cancer J Clin,2008,58(2):71-96.
[2] 王继恒,李世荣.我国结直肠癌筛查和早期诊断十年回顾:1994-2005[J].胃肠病学,2006,11(4):245-250.
[3] Gumaste VV.CT colonograghy can be an adjunct to optical colonoscopy in CRC screening[J].Dig Dis Sci,2009,54(2):212-217.
[4] Luo D,Cambon AC,Wu D,et al.Evaluating the long-term effect of FOBT in colorectal cancer screening[J].Cancer Epidemiol,2012,36(1):e54-e60.
[5] 刘国伟.孔祥毓.大肠癌筛查研究[J].医学综述,2008,14(21):32-49.
[6] 王磊,韩树堂.早期大肠癌及癌前病变中西医治疗概况[J].现代中西医结合杂志,2013,22(19):114-116.
[7] 姜泊,龚伟.如何提高早期大肠癌及癌前病变内镜诊断率[J].广东医学,2011,32(1):1-5.
[8] Labianca R,Beretta GD,Kildani B,et al.Colon cancer[J].Crit Rev Oncol Hematol,2010,74(2):106-133.
[9] Mandel JS,Church TR,Bond JH,et al.The effect of fecal occult-blood screening on the incidence of colorectal cancer[J].N Engl J Med,2000,343(22):1603-1607.
[10] Allison JE,Sakoda LC,Levin TR,et al.Screening for colorectal neoplasms with new fecal occult blood tests:update on performance characteristics[J].J Natl Cancer Inst,2007,99(19):1462-1470.
[11] Oort FA,Terhaar Sive Droste JS,Van Der Hulst RW,et al.Colonoscopy-controlled intra-individual comparisons to screen relevant neoplasia:faecal immunochemical test vs. guaiac-based faecal occult blood test[J].Aliment Pharmacol Ther,2010,31(3):432-439.
[12] Parra-Blanco A,Gimeno-García AZ,Quintero E,et al.Diagnostic accuracy of immunochemical versus guaiac faecal occult blood tests for colorectal cancer screening[J].J Gastroenterol,2010,45(7):703-712.
[13] 庄璐,李兆申,蔡全才.犬肠癌筛查方法研究新进展[J].胃肠病学和肝病学杂志,2014,23(1):1-4.
(收稿日期:2014-08-28 本文编辑:许俊琴) (黄珏 田相龙 宋冬霞)