化痰活血平肝方联合西药治疗顽固性高血压的临床效果(1)
[摘要] 目的 探讨化痰活血平肝方联合西药治疗顽固性高血压的临床效果。 方法 选取2013年5月～2014年5月本院收治的100例顽固性高血压患者，将其分为观察组、对照组，每组50例。对照组患者接受西药治疗，观察组患者在对照组基础上联合化痰活血平肝方治疗。比较两组的临床疗效、治疗后的收缩压、舒张压下降值。 结果 观察组的总有总效率为96.0%，对照组为76.0%，两组比较，差异有统计学意义(χ2=16.61，P<0.01)。观察组治疗后收缩压下降(30.12±9.23)mm Hg，对照组下降(16.13±10.24)mm Hg，两组比较，差异有统计学意义(t=7.18，P<0.01)；观察组治疗后舒张压下降(21.52±8.63)mm Hg，对照组下降(10.42±8.53)mm Hg，两组比较，差异有统计学意义(t=6.47，P<0.01)。 结论 化痰活血平肝方联合西药能有效治疗顽固性高血压，使收缩压、舒张压明显下降。
[关键词] 化痰活血平肝方；中西医结合；顽固性高血压
[中图分类号] R544.1 [文献标识码] A [文章编号] 1674-4721(2015)07(b)-0142-03
[Abstract] Objective To explore the clinical effect of of phlegm-dissolving，blood-activating and liver-calming prescription combined with western medicine in the treatment of refractory hypertension. Methods From May 2013 to May 2014，100 patients with refractory hypertension treated in our hospital were selected and they were divided into observation group and control group，and there were 50 cases in each group.Control group was treated with western medicine，while observation group was treated with phlegm-dissolving，blood-activating and liver-calming prescription on the basis of control group.The clinical efficacy，reduction value of systolic and diastolic blood pressure after treatment between two groups was compared respectively. Results The total effective rate in observation group reached 96.0%，while in the control group，only 76.0% and there was a statistical difference between two groups (χ2=16.61，P<0.01).Systolic pressure was reduced by (30.12±9.23) mm Hg after treatment in observation group，while in control group，the systolic pressure was reduced by (16.13±10.24) mm Hg，which displayed a statistical difference (t=7.18，P<0.01)；in observation group，diastolic blood pressure decreased by (21.52±8.63) mm Hg，while in control group，diastolic blood pressure decreased by (10.42±8.53) mm Hg，which displayed a statistical difference (t=6.47，P<0.01). Conclusion Phlegm-dissolving，blood-activating and liver-calming prescription combined with western medicine can effectively treat refractory hypertension，and can obviously decrease diastolic pressure and systolic pressure.
[Key words] Phlegm-dissolving，blood-activating and liver-calming prescription；Integration of traditional Chinese and western medicine；Refractory hypertension
高血压是心血管常见疾病，该病多发于中老年患者[1-2]。随着人们生活方式的改变，高血压患者数与日俱增，且有年轻化趋势[3-6]。多数患者在应用相应药物后能较好地控制血压，减少血压过高对心血管的损害，但仍存在许多患者在应用3种及3种以上药物后仍不能很好控制血压的问题。该类患者需应用包括利尿剂在内的至少4种降压药物才能控制血压，此类高血压疾病为顽固性高血压[7]。顽固性高血压严重损害患者的心脑血管健康，不仅容易造成心力衰竭等慢性并发症，还易造成脑出血等急性并发症，甚至猝死。本研究主要为探讨化痰活血平肝方联合西药治疗顽固性高血压的临床效果，现报道如下。 (宋日辉)
[关键词] 化痰活血平肝方；中西医结合；顽固性高血压
[中图分类号] R544.1 [文献标识码] A [文章编号] 1674-4721(2015)07(b)-0142-03
[Abstract] Objective To explore the clinical effect of of phlegm-dissolving，blood-activating and liver-calming prescription combined with western medicine in the treatment of refractory hypertension. Methods From May 2013 to May 2014，100 patients with refractory hypertension treated in our hospital were selected and they were divided into observation group and control group，and there were 50 cases in each group.Control group was treated with western medicine，while observation group was treated with phlegm-dissolving，blood-activating and liver-calming prescription on the basis of control group.The clinical efficacy，reduction value of systolic and diastolic blood pressure after treatment between two groups was compared respectively. Results The total effective rate in observation group reached 96.0%，while in the control group，only 76.0% and there was a statistical difference between two groups (χ2=16.61，P<0.01).Systolic pressure was reduced by (30.12±9.23) mm Hg after treatment in observation group，while in control group，the systolic pressure was reduced by (16.13±10.24) mm Hg，which displayed a statistical difference (t=7.18，P<0.01)；in observation group，diastolic blood pressure decreased by (21.52±8.63) mm Hg，while in control group，diastolic blood pressure decreased by (10.42±8.53) mm Hg，which displayed a statistical difference (t=6.47，P<0.01). Conclusion Phlegm-dissolving，blood-activating and liver-calming prescription combined with western medicine can effectively treat refractory hypertension，and can obviously decrease diastolic pressure and systolic pressure.
[Key words] Phlegm-dissolving，blood-activating and liver-calming prescription；Integration of traditional Chinese and western medicine；Refractory hypertension
高血压是心血管常见疾病，该病多发于中老年患者[1-2]。随着人们生活方式的改变，高血压患者数与日俱增，且有年轻化趋势[3-6]。多数患者在应用相应药物后能较好地控制血压，减少血压过高对心血管的损害，但仍存在许多患者在应用3种及3种以上药物后仍不能很好控制血压的问题。该类患者需应用包括利尿剂在内的至少4种降压药物才能控制血压，此类高血压疾病为顽固性高血压[7]。顽固性高血压严重损害患者的心脑血管健康，不仅容易造成心力衰竭等慢性并发症，还易造成脑出血等急性并发症，甚至猝死。本研究主要为探讨化痰活血平肝方联合西药治疗顽固性高血压的临床效果，现报道如下。 (宋日辉)