糖皮质激素对慢性阻塞性肺疾病急性加重患者Th1/Th2平衡失调的影响(3)
总之,COPD急性加重期存在Th1/Th2平衡向Th2端漂移的特点,糖皮质激素可改善这种平衡失调。[参考文献]
[1] Shriai T,Suzuki K,Inui N,et al.Th1/Th2 profile in peripheral blood in atopic cough and atopic asthma[J].Clin Exp Allergy,2003,33(1):84-89.
[2] Hodge G,Nairn J,Holmes M,et al.Increased intracellular T helper 1 proinflammatory cytokine production in peripheral blood,bronchoalveolar lavage and intraepithelial T cells of COPD subjects[J].Clin Exp Immunol ......
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