有创无创序贯机械通气抢救重症呼吸衰竭老年患者的有效性与安全性分析(1)
[摘要]目的 探讨有创无创序贯机械通气抢救重症呼吸衰竭老年患者的有效性与安全性。方法 选取2014年12月～2016年3月在本院接受治疗的64例重症呼吸衰竭老年患者为研究对象，按照随机数字表法分为对照组和观察组，每组32例。对照组患者给予传统机械通气疗法治疗，观察组患者接受有创无创序贯机械通气治疗，比较两组患者的血气分析指标、呼吸、心率，治疗用时以及临床效果。结果 观察组患者的PaO2、SpO2明显高于对照组，PaCO2、HR、RR均明显低于对照组(P<0.05)。观察组的总机械通气用时、有创通气用时、住院天数均明显短于对照组，差异有统计学意义(P<0.05)。观察组患者的成功撤机率高于对照组，再次插管率及呼吸机相关肺炎发生率均明显低于对照组(P<0.05)。结论 有创无创序贯机械通气用于抢救重症呼吸衰竭老年患者的效果显著，且具有较高的安全性，值得临床广泛推广应用。
[关键词]有创无创序贯机械通气；抢救；重症呼吸衰竭；老年患者
[中图分类号] R563.8 [文献标识码] A [文章编号] 1674-4721(2017)04(a)-0027-03
Safety and efficacy analysis of invasive and non-invasive sequential mechanical ventilation in the treatment of elderly patients with severe respiratory failure
LIU Jian-min
The Second Department，Jiangxi Provincal People′s Hospital，Nanchang 330000，China
[Abstract]Objective To explore the safety and efficacy of invasive and non-invasive sequential mechanical ventilation in the treatment of elderly patients with severe respiratory failure.Methods 64 elderly patients with severe respiratory failure treated in our hospital from December 2014 to March 2016 were selected as study object.Patients were divided into control group and observation group according to random number table method，and each group had 32 cases.The control group was given conventional mechanical ventilation and the observation group was given invasive and non-invasive sequential mechanical ventilation.The blood gas indexes，respiratory (RR) and heart rate (HR)，therapeutic time and clinical effect between two groups were compared.Results The PaO2 and SpO2 in observation group were obviously higher than those in control group，while PaCO2，HR and RR were obviously lower than those in control group (P<0.05).Total mechanical ventilation time，invasive ventilation time and hospital stay in observation group were shorter than those in control group，and the difference was significant (P<0.05).Rate of successful weaning in observation group was higher than that of control group，and the rate of reintubation and ventilator associated pneumonia were lower than those of control group (P<0.05).Conclusion Invasive and non-invasive sequential mechanical ventilation in the treatment of elderly patients with severe respiratory failure has a obvious effect，which with higher safety and is worth to be widely used in clinic.
[Key words]Invasive and non-invasive sequential mechanical ventilation；Rescue；Severe respiratory failure；Elderly patient
臨床救治各类呼吸衰竭患者常采用机械通气[1]，该项治疗措施可以维持有效的肺泡通气量范围，且可有效改善肺部气体交换，从而挽救患者的生命[2]。我院为提升重症呼吸衰竭患者的抢救有效率，特为部分患者开展有创无创序贯机械通气治疗，获得了理想的治疗效果，详细报道如下。 (刘建民)
[关键词]有创无创序贯机械通气；抢救；重症呼吸衰竭；老年患者
[中图分类号] R563.8 [文献标识码] A [文章编号] 1674-4721(2017)04(a)-0027-03
Safety and efficacy analysis of invasive and non-invasive sequential mechanical ventilation in the treatment of elderly patients with severe respiratory failure
LIU Jian-min
The Second Department，Jiangxi Provincal People′s Hospital，Nanchang 330000，China
[Abstract]Objective To explore the safety and efficacy of invasive and non-invasive sequential mechanical ventilation in the treatment of elderly patients with severe respiratory failure.Methods 64 elderly patients with severe respiratory failure treated in our hospital from December 2014 to March 2016 were selected as study object.Patients were divided into control group and observation group according to random number table method，and each group had 32 cases.The control group was given conventional mechanical ventilation and the observation group was given invasive and non-invasive sequential mechanical ventilation.The blood gas indexes，respiratory (RR) and heart rate (HR)，therapeutic time and clinical effect between two groups were compared.Results The PaO2 and SpO2 in observation group were obviously higher than those in control group，while PaCO2，HR and RR were obviously lower than those in control group (P<0.05).Total mechanical ventilation time，invasive ventilation time and hospital stay in observation group were shorter than those in control group，and the difference was significant (P<0.05).Rate of successful weaning in observation group was higher than that of control group，and the rate of reintubation and ventilator associated pneumonia were lower than those of control group (P<0.05).Conclusion Invasive and non-invasive sequential mechanical ventilation in the treatment of elderly patients with severe respiratory failure has a obvious effect，which with higher safety and is worth to be widely used in clinic.
[Key words]Invasive and non-invasive sequential mechanical ventilation；Rescue；Severe respiratory failure；Elderly patient
臨床救治各类呼吸衰竭患者常采用机械通气[1]，该项治疗措施可以维持有效的肺泡通气量范围，且可有效改善肺部气体交换，从而挽救患者的生命[2]。我院为提升重症呼吸衰竭患者的抢救有效率，特为部分患者开展有创无创序贯机械通气治疗，获得了理想的治疗效果，详细报道如下。 (刘建民)