[摘要]白血病细胞对化疗药物产生多药耐药(MDR)是化疗失败和疾病复发的主要原因。由于肿瘤细胞MDR作用机制十分复杂，而中药可多靶点、多途径、低毒、高效逆转MDR。作为耐药逆转剂，中药增强耐药肿瘤细胞对化疗药物敏感性成为研究热点。本文就肿瘤细胞MDR复杂机制、中药单体和中药复方逆转MDR的研究进行综述。

    [关键词]中药单体；中药复方；白血病细胞；多药耐药

    [中图分类号] R733.7 [文献标识码] A [文章编号] 1674-4721(2017)08(c)-0011-04

    [Abstract]The main reason of causing failure of chemotherapy and disease recurrence is multidrug resistance (MDR).Because the mechanism of tumor cell MDR action is very complex，traditional Chinese medicine can reverse MDR with multiple targets ......