医用臭氧水灌洗法与痛点注射法联合使用治疗膝关节骨性关节炎的临床研究(1)
[摘要]目的 探讨医用臭氧水灌洗法与痛点注射法联合使用治疗膝关节骨性关节炎的临床效果。方法 选择2015年2月～2016年1月在我院收治的膝关节骨性关节炎患者120例，依据治疗方案的不同分为对照组、观察组，每组60例。对照组实施膝关节腔内玻璃酸钠注射治疗，观察组行医用臭氧水灌洗法与痛点注射法治疗，比较两组治疗第1、4、12周的疼痛情况、膝关节情况以及12个月后的临床疗效。结果 观察组第4周、12周的VAS疼痛评分均低于对照组(P<0.05)，且第1、4周的膝关节评分优于对照组(P<0.05)，观察组的总有效率为96.67%，高于对照组的73.33%(P<0.05)。结论 医用臭氧水灌洗法与痛点注射法联合使用治疗膝关节骨性关节炎的临床效果显著，值得在临床中推广实施。
[关键词]痛点注射法；医用臭氧水灌洗法；临床效果；膝关节骨性关节炎；疼痛
[中图分类号] R684 [文献标识码] A [文章编号] 1674-4721(2017)12(a)-0090-03
[Abstract]Objective To explore the clinical effect of medical ozone water lavage and pain point injection combined treatment of knee osteoarthritis.Methods 120 knee osteoarthritis patients from February 2015 to January 2016 of our hospital were selected as study objects and divided into control group and observation group according to different treatment，each group was 60 cases.The control group was treated with sodium hyaluronate injection in the knee joint cavity.The observation group was treated with medical ozone water lavage combined with pain point injection.The pain situation，knee joint condition after treatment for 1，4 and 12 weeks，and clinical efficacy after treatment for 12 months were compared between the two groups.Results The VAS pain scores of the observation group at fourth weeks and 12 weeks were lower than that of the control group (P<0.05)，and the knee joint score of the first，fourth week was better than that of the control group(P<0.05).The total effective rate of the observation group was 96.67%，which was higher than 73.33% of the control group (P<0.05).Conclusion Medical ozone water lavage combined with pain point injection treating knee osteoarthritis with the significant clinical effec，which is worth popularizing and using in clinical practice.
[Key words]Pain point injection；Medical ozone water lavage；Knee osteoarthritis；Pain
膝關节骨性关节炎为临床中常见慢性骨关节疾病，主要以关节面退行性病变、骨质增生为病变特征，主要临床症状表现为活动障碍、剧烈疼痛等，对患者的生活质量造成严重影响[1]。目前临床中常采取非甾体抗炎药物或玻璃酸钠注射治疗，但临床效果不佳。有研究表明，医用臭氧水灌洗法与痛点注射法联合使用治疗膝关节骨性关节炎的效果显著[2]，本研究为探讨医用臭氧水灌洗法与痛点注射法联合使用治疗膝关节骨性关节炎的效果，现报道如下。
1资料与方法
1.1一般资料
选择2015年2月～2016年1月在我院收治的膝关节骨性关节炎患者120例，依据治疗方案的不同分为对照组、观察组，每组60例。对照组男性33例，女性27例；年龄为45～78岁，平均(67.48±6.14)岁；病程为4个月～12年，平均(6.87±1.45)年。观察组男性34例，女性26例；年龄为43～76岁，平均(67.15±6.24)岁；病程为4个月～11年，平均(6.67±1.43)年。两组患者的一般资料差异无统计学意义(P>0.05)，具有可比性。
膝关节骨性关节炎诊断标准[3]。①30 d内膝关节反复疼痛；②X线下关节间隙狭窄、囊性病变或关节缘形成骨赘；③关节液黏稠且清亮，WBC在2000个/ml以上；年龄≥40岁，晨僵时间<0.5 h；④活动时有强烈骨擦音。
纳入标准[4]：①符合膝关节骨性关节炎诊断标准的患者；②治疗依从性高且接受随访的患者；③对治疗药物无变态反应的患者；④所有患者均签订自愿研究同意书并经相关医学伦理委员会批准。, 百拇医药(陈晓龙 钟响明 李晓阳)
[关键词]痛点注射法；医用臭氧水灌洗法；临床效果；膝关节骨性关节炎；疼痛
[中图分类号] R684 [文献标识码] A [文章编号] 1674-4721(2017)12(a)-0090-03
[Abstract]Objective To explore the clinical effect of medical ozone water lavage and pain point injection combined treatment of knee osteoarthritis.Methods 120 knee osteoarthritis patients from February 2015 to January 2016 of our hospital were selected as study objects and divided into control group and observation group according to different treatment，each group was 60 cases.The control group was treated with sodium hyaluronate injection in the knee joint cavity.The observation group was treated with medical ozone water lavage combined with pain point injection.The pain situation，knee joint condition after treatment for 1，4 and 12 weeks，and clinical efficacy after treatment for 12 months were compared between the two groups.Results The VAS pain scores of the observation group at fourth weeks and 12 weeks were lower than that of the control group (P<0.05)，and the knee joint score of the first，fourth week was better than that of the control group(P<0.05).The total effective rate of the observation group was 96.67%，which was higher than 73.33% of the control group (P<0.05).Conclusion Medical ozone water lavage combined with pain point injection treating knee osteoarthritis with the significant clinical effec，which is worth popularizing and using in clinical practice.
[Key words]Pain point injection；Medical ozone water lavage；Knee osteoarthritis；Pain
膝關节骨性关节炎为临床中常见慢性骨关节疾病，主要以关节面退行性病变、骨质增生为病变特征，主要临床症状表现为活动障碍、剧烈疼痛等，对患者的生活质量造成严重影响[1]。目前临床中常采取非甾体抗炎药物或玻璃酸钠注射治疗，但临床效果不佳。有研究表明，医用臭氧水灌洗法与痛点注射法联合使用治疗膝关节骨性关节炎的效果显著[2]，本研究为探讨医用臭氧水灌洗法与痛点注射法联合使用治疗膝关节骨性关节炎的效果，现报道如下。
1资料与方法
1.1一般资料
选择2015年2月～2016年1月在我院收治的膝关节骨性关节炎患者120例，依据治疗方案的不同分为对照组、观察组，每组60例。对照组男性33例，女性27例；年龄为45～78岁，平均(67.48±6.14)岁；病程为4个月～12年，平均(6.87±1.45)年。观察组男性34例，女性26例；年龄为43～76岁，平均(67.15±6.24)岁；病程为4个月～11年，平均(6.67±1.43)年。两组患者的一般资料差异无统计学意义(P>0.05)，具有可比性。
膝关节骨性关节炎诊断标准[3]。①30 d内膝关节反复疼痛；②X线下关节间隙狭窄、囊性病变或关节缘形成骨赘；③关节液黏稠且清亮，WBC在2000个/ml以上；年龄≥40岁，晨僵时间<0.5 h；④活动时有强烈骨擦音。
纳入标准[4]：①符合膝关节骨性关节炎诊断标准的患者；②治疗依从性高且接受随访的患者；③对治疗药物无变态反应的患者；④所有患者均签订自愿研究同意书并经相关医学伦理委员会批准。, 百拇医药(陈晓龙 钟响明 李晓阳)