局部氧疗治疗新生儿尿布皮炎效果的Meta分析(1)
[摘要]目的 系統评价局部氧疗治疗新生儿尿布皮炎的效果。方法 检索The Cochrane Library、PubMed、Embase、中国生物医学数据库、中国知网数据库、维普数据库和万方数据库，检索时间从建库至2017年6月，收集有关局部氧疗或者局部氧疗联合其他治疗方法治疗新生儿尿布皮炎的随机对照试验，根据Cochrane 手册5.1.0进行质量评价后，提取文献数据，采用RevMan 5.3软件进行Meta分析。结果 共纳入16个随机对照试验，合计2317例患者。Meta分析结果显示，在总有效率方面，局部氧疗或者局部氧疗联合其他治疗方法明显优于其他治疗方法组，差异有统计学意义[OR=9.07，95%CI(6.01，13.70)，P<0.00001]；在治愈时间方面，局部氧疗或者局部氧疗联合其他治疗方法组明显优于其他治疗方法组，且差异有统计学意义[MD=-1.96，95%CI(-2.85，-1.06)，P<0.00001]；在满意度方面，有一项研究提示局部氧疗组比对照组患儿和护理人员满意率高；在不良反应方面，不会增加不良反应的发生。结论 现有研究提示，应用局部氧疗可提高治疗总有效率，缩短治愈时间，提高患儿和护理人员的满意度，且不会增加不良反应的发生。
[关键词]Meta分析；局部氧疗；新生儿；尿布皮炎；系统评价；随机对照试验
[中图分类号] R459.6 [文献标识码] A [文章编号] 1674-4721(2018)8(b)-0021-05
Meta-analysis of effect of topical oxygen therapy treating neonatal diaper dermatitis
YE Xin-xin1 ZHAN Chen-ju2 LIU Qi-xi2 ZENG Lin-miao3 XU Zhong-bo4
1. School of Nursing， Fujian University of Traditional Chinese Medicine， Fujian Province， Fuzhou 350122， China； 2. Department of Nursing， Mindong Hospital of Ningde City， Fujian Province， Ningde 355000， China； 3. Department of Respiratory Medicine，Mindong Hospital of Ningde City， Fujian Province， Ningde 355000， China； 4. Department of Emergency， Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine， Jiangxi Province， Nanchang 330006， China
[Abstract] Objective To systematically evaluate the effect of topical oxygen therapy treating neonatal diaper dermatitis. Methods The Cochrane Library， PubMed， Embase， China Biomedical Database， China Knowledge Database， VIP Database and Wanfang Database were searched. The search date was from database construction to June 2017. Randomized controlled trials of topical oxygen therapy or topical oxygen therapy combined with other treatments treating neonatal diaper dermatitis were collected. After evaluating the quality according to the Cochrane manual 5.1.0， literature data were extracted and Meta analysis was performed using RevMan 5.3 software. Results A total of 16 randomized controlled trials were included in， and there were 2317 patients. The results of Meta-analysis show that： in terms of the total effective rate， topical oxygen therapy or topical oxygen therapy combined with other treatments methods was significantly better than other treatments with a significant difference (OR=9.07， 95% CI [6.01， 13.70]， P<0.00001)； in the healing time， topical oxygen therapy or topical oxygen therapy combined with other treatments methods was significantly better than other treatments with a significant difference (MD=-1.96， 95% CI [-2.85， -1.06] ， P<0.00001)； in terms of satisfaction degree， one study suggested that the satisfaction rate of pediatric patients and nursing staff in the local oxygen therapy group was higher than that of control group； in adverse reactions， it did not increase the occurrence of adverse reactions. Conclusion Existing research shows that application of topical oxygen therapy can improve the total effective rate of treating， shorten the healing time， increase the satisfaction degree of pediatric patients and nursing staff， and it does not increase the occurrence of adverse reactions., 百拇医药(叶欣欣 詹陈菊 刘琪希 曾林淼 许忠波)
[关键词]Meta分析；局部氧疗；新生儿；尿布皮炎；系统评价；随机对照试验
[中图分类号] R459.6 [文献标识码] A [文章编号] 1674-4721(2018)8(b)-0021-05
Meta-analysis of effect of topical oxygen therapy treating neonatal diaper dermatitis
YE Xin-xin1 ZHAN Chen-ju2 LIU Qi-xi2 ZENG Lin-miao3 XU Zhong-bo4
1. School of Nursing， Fujian University of Traditional Chinese Medicine， Fujian Province， Fuzhou 350122， China； 2. Department of Nursing， Mindong Hospital of Ningde City， Fujian Province， Ningde 355000， China； 3. Department of Respiratory Medicine，Mindong Hospital of Ningde City， Fujian Province， Ningde 355000， China； 4. Department of Emergency， Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine， Jiangxi Province， Nanchang 330006， China
[Abstract] Objective To systematically evaluate the effect of topical oxygen therapy treating neonatal diaper dermatitis. Methods The Cochrane Library， PubMed， Embase， China Biomedical Database， China Knowledge Database， VIP Database and Wanfang Database were searched. The search date was from database construction to June 2017. Randomized controlled trials of topical oxygen therapy or topical oxygen therapy combined with other treatments treating neonatal diaper dermatitis were collected. After evaluating the quality according to the Cochrane manual 5.1.0， literature data were extracted and Meta analysis was performed using RevMan 5.3 software. Results A total of 16 randomized controlled trials were included in， and there were 2317 patients. The results of Meta-analysis show that： in terms of the total effective rate， topical oxygen therapy or topical oxygen therapy combined with other treatments methods was significantly better than other treatments with a significant difference (OR=9.07， 95% CI [6.01， 13.70]， P<0.00001)； in the healing time， topical oxygen therapy or topical oxygen therapy combined with other treatments methods was significantly better than other treatments with a significant difference (MD=-1.96， 95% CI [-2.85， -1.06] ， P<0.00001)； in terms of satisfaction degree， one study suggested that the satisfaction rate of pediatric patients and nursing staff in the local oxygen therapy group was higher than that of control group； in adverse reactions， it did not increase the occurrence of adverse reactions. Conclusion Existing research shows that application of topical oxygen therapy can improve the total effective rate of treating， shorten the healing time， increase the satisfaction degree of pediatric patients and nursing staff， and it does not increase the occurrence of adverse reactions., 百拇医药(叶欣欣 詹陈菊 刘琪希 曾林淼 许忠波)