吸入用布地奈德混悬液治疗小儿哮喘急性发作的效果及对肺功能的影响(1)
[摘要]目的 探讨吸入用布地奈德混悬液治疗小儿哮喘急性发作的效果及对肺功能的影响。方法 选取我院2016年3月～2018年1月收治的50例小儿哮喘急性发作的患儿作为研究对象，按照随机分组的方法分为观察组(25例)和对照组(25例)。对照组采用常规治疗，观察组采用吸入用布地奈德混悬液治疗，比较两组的治疗效果、临床症状改善时间，并比较两组治疗前后肺功能指标改善情况。结果 观察组的治疗有效率为96.00%，明显高于对照组的72.00%，差异有统计学意义(P<0.05);观察组的咳嗽缓解时间、肺哮鸣音消失时间以及气促缓解时间明显短于对照组，治疗后观察组的肺功能各项指标数据也明显高于对照组，差异均有统计学意义(P<0.05)。结论 对小儿哮喘急性发作的治疗，采用吸入用布地奈德混悬液效果较为理想，能快速缓解患儿的临床症状，改善其肺功能，加速患儿恢复，具有重要的临床意义。
[关键词]吸入用布地奈德混悬液;小儿哮喘;急性发作;临床效果;肺功能影响
[中图分类号] R721 [文献标识码] A [文章编号] 1674-4721(2019)2(a)-0162-03
[Abstract] Objective To investigate the effect of Budesonide suspension in the treatment of acute attack of asthma in children and its influence on pulmonary function. Methods Altogcther 50 children with acute attack of asthma in our hospital from March 2016 to January 2018 were selected and randomly divided into observation group (25 cases) and control group (25 cases). The control group was treated with routine treatment. The observation group was treated with Budesonide. The therapeutic effects of the two groups were compared. The improvement time of clinical symptoms and the improvement of pulmonary function before and after treatment were compared. Results The effective rate of the observation group was 96.00%， which was significantly higher than that of the control group (72.00%)， the difference was statistically significant (P<0.05). The cough relief time， the disappearance time of wheezing sound and the relief time of shortness of breath was significantly shorter than that of the control group(P<0.05). After treatment， the indexes of lung function in the observation group were also significantly higher than those in the control group， the differences were statistically significant (P<0.05). Conclusion Budesonide is effective in the treatment of acute asthma in children. It can quickly relieve the clinical symptoms， improve the pulmonary function and accelerate the recovery of children with asthma.
[Key words] Budesonide; Pediatric asthma; Acute attack; Clinical effect; Pulmonary function effect
哮喘屬于临床中常见的疾病类型，严重影响患者的身体健康。现今，该疾病的发生率也呈上升趋势，其发病因素主要和环境、遗传、气候及生活习惯等有关，而小儿的器官发育不完善，免疫能力及抵抗能力均较弱，因此很容易受到疾病的侵害，引发哮喘，患儿患病后，会出现喘息、气促等症状，而小儿哮喘发展到急性发作期，就会出现呼吸困难、憋喘等症状，严重影响患儿的健康，如果未及时进行治疗，则直接危及其生命，所以有效的治疗方式是保证患儿生命安全的关键，常规的治疗方式为镇咳、化痰、平喘等，虽有一定的治疗效果，但效果并不理想[1]，而本研究主要分析吸入用布地奈德混悬液对小儿哮喘急性发作的效果及对患儿肺功能的影响效果，现报道如下。
1资料与方法
1.1一般资料
选取我院2016年3月～2018年1月收治的50例哮喘急性发作患儿作为研究对象，按照随机分组的方法分为观察组(25例)和对照组(25例)。观察组中，男15例，女10例;年龄1～11岁，平均(4.57±1.22)岁;病程2个月～1年，平均(0.77±0.22)年;轻度哮喘患儿10例，中度哮喘11例，重度4例。对照组中，男14例，女11例;年龄1～10岁，平均(4.62±1.31)岁;病程2个月～1年，平均(0.82±0.21)年;轻度哮喘患儿12例，中度哮喘10例，重度3例。两组的年龄、性别等一般资料比较，差异无统计学意义(P>0.05)，具有可比性。纳入标准：①患儿均符合小儿哮喘的临床诊断标准，并为急性发作期[2];②均经临床症状、X线以及支气管扩张实验确诊;③患儿家长均同意本研究，并签订知情同意书。排除标准：①患有心肝肾功能障碍者;②支气管异物者;③药物过敏者;④不配合治疗者。本研究经医院医学伦理委员会批准。, 百拇医药(黄璜)
[关键词]吸入用布地奈德混悬液;小儿哮喘;急性发作;临床效果;肺功能影响
[中图分类号] R721 [文献标识码] A [文章编号] 1674-4721(2019)2(a)-0162-03
[Abstract] Objective To investigate the effect of Budesonide suspension in the treatment of acute attack of asthma in children and its influence on pulmonary function. Methods Altogcther 50 children with acute attack of asthma in our hospital from March 2016 to January 2018 were selected and randomly divided into observation group (25 cases) and control group (25 cases). The control group was treated with routine treatment. The observation group was treated with Budesonide. The therapeutic effects of the two groups were compared. The improvement time of clinical symptoms and the improvement of pulmonary function before and after treatment were compared. Results The effective rate of the observation group was 96.00%， which was significantly higher than that of the control group (72.00%)， the difference was statistically significant (P<0.05). The cough relief time， the disappearance time of wheezing sound and the relief time of shortness of breath was significantly shorter than that of the control group(P<0.05). After treatment， the indexes of lung function in the observation group were also significantly higher than those in the control group， the differences were statistically significant (P<0.05). Conclusion Budesonide is effective in the treatment of acute asthma in children. It can quickly relieve the clinical symptoms， improve the pulmonary function and accelerate the recovery of children with asthma.
[Key words] Budesonide; Pediatric asthma; Acute attack; Clinical effect; Pulmonary function effect
哮喘屬于临床中常见的疾病类型，严重影响患者的身体健康。现今，该疾病的发生率也呈上升趋势，其发病因素主要和环境、遗传、气候及生活习惯等有关，而小儿的器官发育不完善，免疫能力及抵抗能力均较弱，因此很容易受到疾病的侵害，引发哮喘，患儿患病后，会出现喘息、气促等症状，而小儿哮喘发展到急性发作期，就会出现呼吸困难、憋喘等症状，严重影响患儿的健康，如果未及时进行治疗，则直接危及其生命，所以有效的治疗方式是保证患儿生命安全的关键，常规的治疗方式为镇咳、化痰、平喘等，虽有一定的治疗效果，但效果并不理想[1]，而本研究主要分析吸入用布地奈德混悬液对小儿哮喘急性发作的效果及对患儿肺功能的影响效果，现报道如下。
1资料与方法
1.1一般资料
选取我院2016年3月～2018年1月收治的50例哮喘急性发作患儿作为研究对象，按照随机分组的方法分为观察组(25例)和对照组(25例)。观察组中，男15例，女10例;年龄1～11岁，平均(4.57±1.22)岁;病程2个月～1年，平均(0.77±0.22)年;轻度哮喘患儿10例，中度哮喘11例，重度4例。对照组中，男14例，女11例;年龄1～10岁，平均(4.62±1.31)岁;病程2个月～1年，平均(0.82±0.21)年;轻度哮喘患儿12例，中度哮喘10例，重度3例。两组的年龄、性别等一般资料比较，差异无统计学意义(P>0.05)，具有可比性。纳入标准：①患儿均符合小儿哮喘的临床诊断标准，并为急性发作期[2];②均经临床症状、X线以及支气管扩张实验确诊;③患儿家长均同意本研究，并签订知情同意书。排除标准：①患有心肝肾功能障碍者;②支气管异物者;③药物过敏者;④不配合治疗者。本研究经医院医学伦理委员会批准。, 百拇医药(黄璜)