个性化体重管理对高血压合并高血脂患者的干预效果分析(1)
[摘要]目的 分析个性化体重管理对高血压合并高血脂患者的干预效果。方法 选取2017年7月1日～2018年6月30日在我院体检中心进行体检的100例高血压合并高血脂患者作为研究对象，根据随机数字表法将患者分为对照组和研究组，每组各50例。对照组患者采用传统的健康教育进行干预，研究组患者采用个性化体重管理进行干预。比较两组患者干预前和干预后的体重、体重指数、收缩压、舒张压、总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)、三酰甘油(TG)、高密度脂蛋白胆固醇(HDL-C)、内皮素-1(ET-1)、一氧化氮(NO)。结果 两组患者干预后的体重、体重指数、收缩压、舒張压、TC、LDL-C、TG、ET-1均明显低于干预前，HDL-C、NO均明显高于干预前，差异有统计学意义(P<0.05)。研究组患者干预后的体重、体重指数、收缩压、舒张压、TC、LDL-C、TG、ET-1均明显低于对照组，HDL-C、NO均明显高于对照组，差异有统计学意义(P<0.05)。结论 个性化体重管理可较好地改善高血压合并高血脂患者的体重、体重指数、血压指标、血脂指标和血管内皮功能。
[关键词]高血压；高血脂；体重管理；个性化
[中图分类号] R544.1 [文献标识码] A [文章编号] 1674-4721(2019)4(b)-0038-04
[Abstract] Objective To analyze the effect of personalized weight management on patients with hypertension and hyperlipidemia. Methods A total of 100 patients with hypertension and hyperlipidemia who underwent physical examination in our physical examination center from July 1， 2017 to June 30， 2018 were enrolled in the sdudy. The patients were divided into control group and research group according to the random number table method， with 50 cases in each group. Patients in the control group were treated with traditional health education， and patients in the research group were treated with personalized weight management. Body weight， body mass index， systolic blood pressure， diastolic blood pressure， total cholesterol (TC)， low-density lipoprotein cholesterol (LDL-C)， triglyceride (TG)， high-density lipoprotein cholesterol (HDL-C)， endothelin-1(ET-1)， nitric oxide (NO) before and after intervention were compared between the two groups. Results After intervention， the body weight， body mass index， systolic blood pressure， diastolic blood pressure， TC， LDL-C， TG and ET-1 of the two groups were significantly lower than those before intervention， HDL-C and NO were significantly higher than those before intervention， and the differences were statistically significant (P<0.05). The body weight， body mass index， systolic blood pressure， diastolic blood pressure， TC， LDL-C， TG and ET-1 in the research group after intervention were significantly lower than those in the control group， HDL-C and NO were significantly higher than those in the control group， and the differences were statistically significant (P<0.05). Conclusion Personalized weight management can improve the body weight， body mass index， blood pressure index， blood lipid index and vascular endothelial function of patients with hypertension and hyperlipidemia.
[Key words] Hypertension； Hyperlipidemia； Weight management； Personalization, 百拇医药(林添海 王宇琴 李华萍)
[关键词]高血压；高血脂；体重管理；个性化
[中图分类号] R544.1 [文献标识码] A [文章编号] 1674-4721(2019)4(b)-0038-04
[Abstract] Objective To analyze the effect of personalized weight management on patients with hypertension and hyperlipidemia. Methods A total of 100 patients with hypertension and hyperlipidemia who underwent physical examination in our physical examination center from July 1， 2017 to June 30， 2018 were enrolled in the sdudy. The patients were divided into control group and research group according to the random number table method， with 50 cases in each group. Patients in the control group were treated with traditional health education， and patients in the research group were treated with personalized weight management. Body weight， body mass index， systolic blood pressure， diastolic blood pressure， total cholesterol (TC)， low-density lipoprotein cholesterol (LDL-C)， triglyceride (TG)， high-density lipoprotein cholesterol (HDL-C)， endothelin-1(ET-1)， nitric oxide (NO) before and after intervention were compared between the two groups. Results After intervention， the body weight， body mass index， systolic blood pressure， diastolic blood pressure， TC， LDL-C， TG and ET-1 of the two groups were significantly lower than those before intervention， HDL-C and NO were significantly higher than those before intervention， and the differences were statistically significant (P<0.05). The body weight， body mass index， systolic blood pressure， diastolic blood pressure， TC， LDL-C， TG and ET-1 in the research group after intervention were significantly lower than those in the control group， HDL-C and NO were significantly higher than those in the control group， and the differences were statistically significant (P<0.05). Conclusion Personalized weight management can improve the body weight， body mass index， blood pressure index， blood lipid index and vascular endothelial function of patients with hypertension and hyperlipidemia.
[Key words] Hypertension； Hyperlipidemia； Weight management； Personalization, 百拇医药(林添海 王宇琴 李华萍)