添加乳糖酶与无乳糖奶粉喂养治疗婴幼儿乳糖不耐受的效果对比(1)
[摘要]目的 探討分析添加乳糖酶与无乳糖奶粉喂养治疗婴幼儿乳糖不耐受的效果。方法 选取我院2016年7月～2017年7月收治的106例乳糖不耐受婴幼儿作为研究对象，随机分为对照组和观察组，每组各53例。对照组患儿给予无乳糖喂养，观察组患儿在母乳喂养的基础上添加乳糖酶，对比分析两组患儿的临床治疗效果。结果 观察组患儿的治疗总有效率、临床症状缓解率均高于对照组，差异有统计学意义(P<0.05)。观察组治疗后的排便次数低于对照组，体重高于对照组，差异有统计学意义(P<0.05)。观察组的止泻时间、腹胀缓解时间、吐奶消失时间、住院时间均短于对照组，临床症状评分低于对照组，微量元素高于对照组，差异有统计学意义(P<0.05)。两组患儿的不良反应发生率比较，差异无统计学意义(P>0.05)。结论 对乳糖不耐受患儿给予乳糖酶治疗，能够减少患儿腹泻的时间和次数，缓解临床症状，改善患儿体内的微量元素，具有显著的临床治疗效果。
[关键词]乳糖酶；无乳糖；喂养治疗；婴幼儿；乳糖不耐受
[中图分类号] R723.19 [文献标识码] A [文章编号] 1674-4721(2019)5(b)-0104-04
Effect comparison of adding lactase and lactose-free milk powder in the treatment of lactose intolerance in infants
SHI Zhuang WENG Zhi-yuan ZHANG You-xiang
Department of Pediatrics， the First People′s Hospital of Guangzhou City， Guangdong Province， Guangzhou 511457， China
[Abstract] Objective To investigate and analyze the effect of adding lactase and lactose-free milk powder in the treatment of lactose intolerance in infants. Methods A total of 106 infants with lactose intolerance admitted to our hospital from July 2016 to July 2017 were selected as research objects and divided into the control group and the observation group， 53 cases in each group. The control group was given lactose-free feeding， and the observation group was additionally administered with lactase on the basis of breastfeeding. The clinical treatment effects of the two groups were compared and analyzed. Results In the observation group， the total effective rate of treatment and the clinical symptom relief rate were higher than those in the control group， with statistically significant differences (P<0.05). The number of bowel movements in the observation group was lower than that in the control group， the body weight of the observation group was higher than that of the control group， with statistically significant difference (P<0.05). The time of diarrhea and bloating remission， the time of recovery of vomiting milk， the length of hospital stay in the observation group were shorter than those in the control group， and the clinical symptom score in the observation group was lower than that in the control group， with statistically significant difference (P<0.05). The levels of trace elements of the observation group were higher than those of the control group， and the differences were statistically significant (P<0.05). There was no significant difference in the incidence rate of adverse reactions between the two groups (P>0.05). Conclusion Administration of lactase to children with lactose intolerance can reduce the time and frequency of diarrhea， relieve clinical symptoms， and improve the trace elements in children， with significant clinical therapeutic effect., http://www.100md.com(石壮 翁志媛 张又祥)
[关键词]乳糖酶；无乳糖；喂养治疗；婴幼儿；乳糖不耐受
[中图分类号] R723.19 [文献标识码] A [文章编号] 1674-4721(2019)5(b)-0104-04
Effect comparison of adding lactase and lactose-free milk powder in the treatment of lactose intolerance in infants
SHI Zhuang WENG Zhi-yuan ZHANG You-xiang
Department of Pediatrics， the First People′s Hospital of Guangzhou City， Guangdong Province， Guangzhou 511457， China
[Abstract] Objective To investigate and analyze the effect of adding lactase and lactose-free milk powder in the treatment of lactose intolerance in infants. Methods A total of 106 infants with lactose intolerance admitted to our hospital from July 2016 to July 2017 were selected as research objects and divided into the control group and the observation group， 53 cases in each group. The control group was given lactose-free feeding， and the observation group was additionally administered with lactase on the basis of breastfeeding. The clinical treatment effects of the two groups were compared and analyzed. Results In the observation group， the total effective rate of treatment and the clinical symptom relief rate were higher than those in the control group， with statistically significant differences (P<0.05). The number of bowel movements in the observation group was lower than that in the control group， the body weight of the observation group was higher than that of the control group， with statistically significant difference (P<0.05). The time of diarrhea and bloating remission， the time of recovery of vomiting milk， the length of hospital stay in the observation group were shorter than those in the control group， and the clinical symptom score in the observation group was lower than that in the control group， with statistically significant difference (P<0.05). The levels of trace elements of the observation group were higher than those of the control group， and the differences were statistically significant (P<0.05). There was no significant difference in the incidence rate of adverse reactions between the two groups (P>0.05). Conclusion Administration of lactase to children with lactose intolerance can reduce the time and frequency of diarrhea， relieve clinical symptoms， and improve the trace elements in children， with significant clinical therapeutic effect., http://www.100md.com(石壮 翁志媛 张又祥)