呼吸操联合雾化治疗慢性阻塞性肺疾病患者的临床效果(1)
[摘要]目的 探讨呼吸操联合雾化治疗慢性阻塞性肺疾病患者的临床效果。方法 选取2016年5月～2018年11月我院收治的60例慢性阻塞性肺疾病患者作为研究对象，采用奇偶数分组法分为参与组和联合组，每组各30例。参与组采用雾化治疗，聯合组采用呼吸操联合雾化治疗。比较两组治疗1个月后的总有效率、临床症状缓解时间、不良反应发生情况、治疗前后动脉血二氧化碳分压(PaCO2)、动脉血氧分压(PaO2)、呼吸流量峰值(PEF)和第1秒用力呼气容积(FEV1)。结果 联合组的治疗总有效率为96.67%，高于参与组的76.67%，差异有统计学意义(P<0.05);联合组的临床症状缓解时间为(2.14±1.04)d，短于参与组的(4.22±1.21)d，差异有统计学意义(P<0.05);联合组治疗后的PaCO2低于治疗前和参与组，PaO2、PEF和FEV1高于治疗前及参与组，差异均有统计学意义(P<0.05);两组的不良反应总发生率比较，差异无统计学意义(P>0.05)。结论 慢性阻塞性肺疾病患者行呼吸操联合雾化治疗的效果显著，能有效改善其肺功能指标，具有较高的临床推广价值。
[关键词]慢性阻塞性肺疾病;呼吸操;雾化;肺功能;二氧化碳分压
[中图分类号] R563 [文献标识码] A [文章编号] 1674-4721(2019)7(c)-0095-03
[Abstract] Objective To explore the clinical effect of respiratory operation combined with nebulization in the treatment of patients with chronic obstructive pulmonary disease. Methods Sixty patients with chronic obstructive pulmonary disease admitted to our hospital from May 2016 to November 2018 were selected as the study subjects， they were divided into participating group and combined group according to odd and even number grouping method， with 30 cases in each group. Participating group was treated with nebulization， while combined group was treated with respiratory operation and nebulization. The total effective rate 1 month after treatment， remission time of clinical symptoms， occurrence of adverse reactions， arterial partial pressure of carbon dioxide (PaCO2)， arterial partial pressure of oxygen (PaO2)， peak respiratory flow (PEF) and forced expiratory volume in the first second (FEV1) before and after treatment were compared between the two groups. Results The total effective rate of the combined group was 96.67%， which was higher than 76.67% of the participating group， the difference was statistically significant (P<0.05). The remission time of clinical symptoms in the combined group was (2.14±1.04) days， which was shorter than (4.22±1.21) days in the participating group， the difference was statistically significant (P<0.05). PaCO2 in the combined group after treatment was lower than that before treatment and in the participating group， PaO2， PEF and FEV1 were significantly higher than those before treatment and in the participating group， the differences were statistically significant (P<0.05). There was no significant difference in the total incidence of adverse reactions between the two groups (P>0.05). Conclusion Respiratory operation combined with nebulization therapy in the treatment of patients with chronic obstructive pulmonary disease has a significant effect， can effectively improve their lung function indicators， and has a high clinical popularization value., http://www.100md.com(丁一梅)
[关键词]慢性阻塞性肺疾病;呼吸操;雾化;肺功能;二氧化碳分压
[中图分类号] R563 [文献标识码] A [文章编号] 1674-4721(2019)7(c)-0095-03
[Abstract] Objective To explore the clinical effect of respiratory operation combined with nebulization in the treatment of patients with chronic obstructive pulmonary disease. Methods Sixty patients with chronic obstructive pulmonary disease admitted to our hospital from May 2016 to November 2018 were selected as the study subjects， they were divided into participating group and combined group according to odd and even number grouping method， with 30 cases in each group. Participating group was treated with nebulization， while combined group was treated with respiratory operation and nebulization. The total effective rate 1 month after treatment， remission time of clinical symptoms， occurrence of adverse reactions， arterial partial pressure of carbon dioxide (PaCO2)， arterial partial pressure of oxygen (PaO2)， peak respiratory flow (PEF) and forced expiratory volume in the first second (FEV1) before and after treatment were compared between the two groups. Results The total effective rate of the combined group was 96.67%， which was higher than 76.67% of the participating group， the difference was statistically significant (P<0.05). The remission time of clinical symptoms in the combined group was (2.14±1.04) days， which was shorter than (4.22±1.21) days in the participating group， the difference was statistically significant (P<0.05). PaCO2 in the combined group after treatment was lower than that before treatment and in the participating group， PaO2， PEF and FEV1 were significantly higher than those before treatment and in the participating group， the differences were statistically significant (P<0.05). There was no significant difference in the total incidence of adverse reactions between the two groups (P>0.05). Conclusion Respiratory operation combined with nebulization therapy in the treatment of patients with chronic obstructive pulmonary disease has a significant effect， can effectively improve their lung function indicators， and has a high clinical popularization value., http://www.100md.com(丁一梅)