双亚苄基哌啶与蛋白酶体抑制剂下调ADRM1表达诱导HL60细胞凋亡(4)
[15]Anchoori RK，Karanam B，Peng S，et al.A bis-benzylidine piperidone targeting proteasome ubiquitin receptor RPN13/ADRM1 as a therapy for cancer[J].Cancer Cell，2013，24：791-805.
[16]Lu X，Zhou C，Li R，et al.Long noncoding RNA AFAP1-AS1 promoted tumor growth and invasion in cholangiocarcinoma[J].Cell Physiol Biochem，2017，42：222-230.
[17]Song Y，Park PMC，Wu L，et al.Development and preclinical validation of a novel covalent ubiquitin receptor Rpn13 degrader in multiple myeloma[J].Leukemia，2019[Epub ahead of print]
[18]Anchoori RK，Jiang R，Peng S，et al.Covalent Rpn13-binding inhibitors for the treatment of ovarian cancer[J].ACS Omega，2018，3(9)：11 917-11 929.
[19]Yu GY，Wang X，Zheng SS，et al.RA190，a proteasome subunit ADRM1 inhibitor，suppresses intrahepatic cholangiocarcinoma by inducing NF-κB-mediated cell apoptosis[J].Cell Physiol Biochem，2018，47(3)：1152-1166.
[20]Lu X，Nowicka U，Sridharan V，et al.Structure of the Rpn13-Rpn2 complex provides insights for Rpn13 and Uch37 as anticancer targets[J].Nat Commun，2017，8：15 540.
(收稿日期：2019-04-24 本文編辑：许俊琴), http://www.100md.com(郑晓辉 王玉孝 隋华秀)
[16]Lu X，Zhou C，Li R，et al.Long noncoding RNA AFAP1-AS1 promoted tumor growth and invasion in cholangiocarcinoma[J].Cell Physiol Biochem，2017，42：222-230.
[17]Song Y，Park PMC，Wu L，et al.Development and preclinical validation of a novel covalent ubiquitin receptor Rpn13 degrader in multiple myeloma[J].Leukemia，2019[Epub ahead of print]
[18]Anchoori RK，Jiang R，Peng S，et al.Covalent Rpn13-binding inhibitors for the treatment of ovarian cancer[J].ACS Omega，2018，3(9)：11 917-11 929.
[19]Yu GY，Wang X，Zheng SS，et al.RA190，a proteasome subunit ADRM1 inhibitor，suppresses intrahepatic cholangiocarcinoma by inducing NF-κB-mediated cell apoptosis[J].Cell Physiol Biochem，2018，47(3)：1152-1166.
[20]Lu X，Nowicka U，Sridharan V，et al.Structure of the Rpn13-Rpn2 complex provides insights for Rpn13 and Uch37 as anticancer targets[J].Nat Commun，2017，8：15 540.
(收稿日期：2019-04-24 本文編辑：许俊琴), http://www.100md.com(郑晓辉 王玉孝 隋华秀)