无创呼吸机联合布地奈德雾化治疗慢性阻塞性肺疾病并呼吸衰竭的临床效果(1)
[摘要]目的 探討无创呼吸机联合布地奈德雾化治疗在慢性阻塞性肺疾病并呼吸衰竭患者中的应用效果。方法 选取2013年1月～2015年5月海珠区中医医院收治的40例慢性阻塞性肺疾病并呼吸衰竭的患者作为研究对象，按照信封随机分组方法将其分为常规组(19例)与实验组(21例)。常规组患者采用常规的方法治疗，实验组患者则在常规组的基础上采用无创呼吸机治疗。比较两组患者的治疗总有效率、血气分析指标[二氧化碳分压(PaCO2)、动脉氧分压(PaO2)]、呼吸频率(RR)、心率(HR)。结果 实验组患者的治疗总有效率(95.24%)高于常规组(57.89%)，差异有统计学意义(P<0.05)。治疗前，两组患者的PaCO2、PaO2、RR、HR比较，差异无统计学意义(P>0.05);治疗后，两组患者的PaCO2均低于本组治疗前，PaO2均高于本组治疗前，RR、HR均慢于本组治疗前，差异有统计学意义(P<0.05);实验组患者治疗后的PaCO2低于常规组，PaO2高于常规组，RR、HR慢于常规组，差异均有统计学意义(P<0.05)。结论 对慢性阻塞性肺疾病并呼吸衰竭患者在常规治疗的基础上采取无创呼吸机联合布地奈德雾化治疗，能够提升治疗有效率，改善血气状况，减缓RR、HR，值得临床应用推广。
[关键词]无创呼吸机;布地奈德;慢性阻塞性肺疾病;呼吸衰竭;疗效
[中图分类号] R563.9 [文献标识码] A [文章编号] 1674-4721(2019)11(c)-0094-04
Clinical effect of non-invasive ventilator combined with Budesonide atomization in the treatment of chronic obstructive pulmonary disease with respiratory failure
ZHANG Ying1 WANG Xiu-qiong2
1. Department of Internal Pediatrics， Haizhu District Women and Child Care Hospital in Guangzhou City， Guangdong Province， Guangzhou 510250， China; 2. Department of Internal Medicine， Haizhu District Hospital of Traditional Chinese Medicinel in Guangzhou City， Guangdong Province， Guangzhou 510220， China
[Abstract] Objective To explore the application effect of non-invasive ventilator combined with Budesonide atomization therapy in patients with chronic obstructive pulmonary disease and respiratory failure. Methods Forty patients with chronic obstructive pulmonary disease complicated with respiratory failure admitted to Haizhu District Hospital of Traditional Chinese Medicine from January 2013 to May 2015 were selected as the research objects and randomly divided into conventional group (19 cases) and experimental group (21 cases) according to envelope grouping method. Patients in the conventional group were treated with conventional methods， while patients in the experimental group were treated with non-invasive ventilator on the basis of the conventional group. The total effective rate of treatment， blood gas analysis indexes (carbon dioxide partial pressure [PaCO2]， arterial oxygen partial pressure [PaO2])， respiratory rate (RR)， heart rate (HR) were compared between the two groups. Results The total effective rate of the patients in the experimental group (95.24%) was higher than that in the conventional group (57.89%)， and the difference was statistically significant (P<0.05). Before treatment， there were no significant difference in PaCO2， PaO2， RR and HR between the two groups (P>0.05). After treatment， PaCO2 of the two groups of patients was lower than that before treatment， PaO2 was higher than that before treatment， RR and HR were slower than those before treatment， the differences were statistically significant (P<0.05). After treatment， PaCO2 in the experimental group was lower than that in the conventional group， PaO2 was higher than that in the conventional group， RR and HR were slower than those in the conventional group， and the differences were statistically significant (P<0.05). Conclusion For patients with chronic obstructive pulmonary disease and respiratory failure， non-invasive ventilator combined with Budesonide atomization therapy based on conventional therapy can improve the treatment efficiency， improve blood gas status， slow RR and HR， and is worthy of clinical application and promotion., http://www.100md.com(张莹 王秀琼)
[关键词]无创呼吸机;布地奈德;慢性阻塞性肺疾病;呼吸衰竭;疗效
[中图分类号] R563.9 [文献标识码] A [文章编号] 1674-4721(2019)11(c)-0094-04
Clinical effect of non-invasive ventilator combined with Budesonide atomization in the treatment of chronic obstructive pulmonary disease with respiratory failure
ZHANG Ying1 WANG Xiu-qiong2
1. Department of Internal Pediatrics， Haizhu District Women and Child Care Hospital in Guangzhou City， Guangdong Province， Guangzhou 510250， China; 2. Department of Internal Medicine， Haizhu District Hospital of Traditional Chinese Medicinel in Guangzhou City， Guangdong Province， Guangzhou 510220， China
[Abstract] Objective To explore the application effect of non-invasive ventilator combined with Budesonide atomization therapy in patients with chronic obstructive pulmonary disease and respiratory failure. Methods Forty patients with chronic obstructive pulmonary disease complicated with respiratory failure admitted to Haizhu District Hospital of Traditional Chinese Medicine from January 2013 to May 2015 were selected as the research objects and randomly divided into conventional group (19 cases) and experimental group (21 cases) according to envelope grouping method. Patients in the conventional group were treated with conventional methods， while patients in the experimental group were treated with non-invasive ventilator on the basis of the conventional group. The total effective rate of treatment， blood gas analysis indexes (carbon dioxide partial pressure [PaCO2]， arterial oxygen partial pressure [PaO2])， respiratory rate (RR)， heart rate (HR) were compared between the two groups. Results The total effective rate of the patients in the experimental group (95.24%) was higher than that in the conventional group (57.89%)， and the difference was statistically significant (P<0.05). Before treatment， there were no significant difference in PaCO2， PaO2， RR and HR between the two groups (P>0.05). After treatment， PaCO2 of the two groups of patients was lower than that before treatment， PaO2 was higher than that before treatment， RR and HR were slower than those before treatment， the differences were statistically significant (P<0.05). After treatment， PaCO2 in the experimental group was lower than that in the conventional group， PaO2 was higher than that in the conventional group， RR and HR were slower than those in the conventional group， and the differences were statistically significant (P<0.05). Conclusion For patients with chronic obstructive pulmonary disease and respiratory failure， non-invasive ventilator combined with Budesonide atomization therapy based on conventional therapy can improve the treatment efficiency， improve blood gas status， slow RR and HR， and is worthy of clinical application and promotion., http://www.100md.com(张莹 王秀琼)