丙戊酸对食管癌细胞增殖凋亡的影响及其抗肿瘤活性机制的研究(5)
[15]Fulda S.Modulation of TRAIL-induced apoptosis by HDAC inhibitors[J].Curr Cancer Drug Targets，2008，8(2)：132-140.
[16]Zhou H，Cai Y，Liu D，et al.Pharmacological or transcriptional inhibition of both HDAC1 and 2 leads to cell cycle blockage and apoptosis via p21Waf1/Cip1 and p19INK4d upregulation in hepatocellular carcinoma[J].Cell Prolif，2018，51(3)：e12447.
[17]Arts J，King P，Marien A，et al.JNJ-26481585，a novel "second-generation" oral histone deacetylase inhibitor，shows broad-spectrum preclinical antitumoral activity[J].Clin Cancer Res，2009，15(22)：6841-6851.
[18]Witt O，Sand K，Pekrun A.Butyrate induced erythroid differentiation of human K562 cells involves inhibition of ERK and activation of p38 MAP kinase pathways[J].Blood，2000， 95(7)：2391-2396.
[19]Peng Z，Guo Z，Ying W，et al.Histone deacetylase inhibitors inhibit the proliferation of gallbladder carcinoma cells by suppressing AKT/mTOR signaling[J].PLoS One，2015，10(8)：e136193.
(收稿日期：2020-02-14 本文編辑：任秀兰)
[基金项目]福建省自然科学基金项目(2017J01223)
通讯作者, 百拇医药(杨鲸蓉 柳亚明 张锦灿 曾志勇)
[16]Zhou H，Cai Y，Liu D，et al.Pharmacological or transcriptional inhibition of both HDAC1 and 2 leads to cell cycle blockage and apoptosis via p21Waf1/Cip1 and p19INK4d upregulation in hepatocellular carcinoma[J].Cell Prolif，2018，51(3)：e12447.
[17]Arts J，King P，Marien A，et al.JNJ-26481585，a novel "second-generation" oral histone deacetylase inhibitor，shows broad-spectrum preclinical antitumoral activity[J].Clin Cancer Res，2009，15(22)：6841-6851.
[18]Witt O，Sand K，Pekrun A.Butyrate induced erythroid differentiation of human K562 cells involves inhibition of ERK and activation of p38 MAP kinase pathways[J].Blood，2000， 95(7)：2391-2396.
[19]Peng Z，Guo Z，Ying W，et al.Histone deacetylase inhibitors inhibit the proliferation of gallbladder carcinoma cells by suppressing AKT/mTOR signaling[J].PLoS One，2015，10(8)：e136193.
(收稿日期：2020-02-14 本文編辑：任秀兰)
[基金项目]福建省自然科学基金项目(2017J01223)
通讯作者, 百拇医药(杨鲸蓉 柳亚明 张锦灿 曾志勇)