CT引导经皮微波消融治疗早期原发性肝癌的临床效果(1)
[摘要]目的 探讨CT引导经皮微波消融(MWA)治疗早期原发性肝癌的临床效果。方法 选取2013年1月～2016年7月我院收治的86例早期原发性肝癌患者作为研究对象，按照电脑随机法将其分为干预组与对照组，每组各43例。干预组患者采用CT引导经皮微波消融治疗方法，对照组患者采用常规肝动脉化疗栓塞治疗方法。比较两组患者的近期疗效、远期疗效、不良反应发生情况。结果 干预组患者的治疗总有效率为81.40%，高于对照组的55.81%，差异有统计学意义(P<0.05);两组患者的不良反应总发生率比较，差异无统计学意义(P>0.05)。两组患者的1年生存率比较，差异无统计学意义(P>0.05);干预组患者的2年生存率与3年生存率均高于对照组，差异有统计学意义(P<0.05)。结论 CT引导下MWA治疗早期原发性肝癌的近期疗效乐观，不良反应发生率低，远期疗效较好。
[关键词]经皮微波消融治疗;原发性肝癌;不良反应;恶性肿瘤;肝硬化
[中图分类号] R734.2 [文献标识码] A [文章编号] 1674-4721(2020)5(c)-0052-04
Clinical effect of CT-guided percutaneous microwave ablation on treatment of early primary hepatic carcinoma
WU Li-gang ZENG Han-qiang
Department of Interventional Therapy， Dongguan People′s Hospital， Guangdong Province， Dongguan 523000， China
[Abstract] Objective To study the clinical effect of CT-guided percutaneous microwave ablation (MWA) on treatment of early primary hepatic carcinoma. Methods A total of 86 early primary hepatic carcinoma patients treated in our hospital from January 2013 to July 2016 were selected as research subjects. According to the computer random method， patients were assigned to intervention group (43 cases) and control group (43 cases). The intervention group was treated with CT-guided percutaneous MWA， the control group was treated with conventional transcatheter arterial chemoembolization. The short-term efficacy， long-term efficacy and adverse reactions were compared. Results The total effective rate in intervention group was 81.40%， which was higher than that of control group (55.81%)， with statistically significant difference (P<0.05). The total incidence of adverse reactions between groups showed no statistically significant difference (P>0.05). One-year survival rate between groups showed no statistically significant difference (P>0.05). Two-year and three-year survival rates in intervention group were higher than those of control group， with statistically significant differences (P<0.05). Conclusion For early primary hepatic carcinoma patients， CT-guided percutaneous MWA has better short-term and long-term efficacy， and lower adverse event rate.
[Key words] Percutaneous microwave ablation; Primary liver cancer; Adverse reactions; Malignant tumor; Liver cirrhosis
原發性肝癌是常见的恶性肿瘤疾病，有资料显示，我国新发肝癌患者以每年11万人数的速度增长，而流行病学调查结果表明肝癌疾病早期起病隐匿，多无特异性临床表现，且疾病发展速度快，大部分患者出现明显症状时已经进入中晚期[1]。我国大部分肝癌疾病是由肝硬化发展而来，患者普遍健康状态较差，病灶位于不同叶段，部分病灶位置可能靠近大血管等，部分原发性肝癌患者年龄较大，可能同时合并其它心脑血管疾病与糖尿病，诸多因素限制下导致患者错过最佳外科手术切除时机[2-3]。原发性肝癌疾病的临床表现包括肝区疼痛、乏力、腹胀、腹水、黄疸、恶病质表现，患病后会降低患者生存质量。本研究选取我院收治的86例早期原发性肝癌患者作为研究对象，分析CT引导经皮微波消融(MWA)的治疗效果，现报道如下。, 百拇医药(吴立刚 曾汉强)
[关键词]经皮微波消融治疗;原发性肝癌;不良反应;恶性肿瘤;肝硬化
[中图分类号] R734.2 [文献标识码] A [文章编号] 1674-4721(2020)5(c)-0052-04
Clinical effect of CT-guided percutaneous microwave ablation on treatment of early primary hepatic carcinoma
WU Li-gang ZENG Han-qiang
Department of Interventional Therapy， Dongguan People′s Hospital， Guangdong Province， Dongguan 523000， China
[Abstract] Objective To study the clinical effect of CT-guided percutaneous microwave ablation (MWA) on treatment of early primary hepatic carcinoma. Methods A total of 86 early primary hepatic carcinoma patients treated in our hospital from January 2013 to July 2016 were selected as research subjects. According to the computer random method， patients were assigned to intervention group (43 cases) and control group (43 cases). The intervention group was treated with CT-guided percutaneous MWA， the control group was treated with conventional transcatheter arterial chemoembolization. The short-term efficacy， long-term efficacy and adverse reactions were compared. Results The total effective rate in intervention group was 81.40%， which was higher than that of control group (55.81%)， with statistically significant difference (P<0.05). The total incidence of adverse reactions between groups showed no statistically significant difference (P>0.05). One-year survival rate between groups showed no statistically significant difference (P>0.05). Two-year and three-year survival rates in intervention group were higher than those of control group， with statistically significant differences (P<0.05). Conclusion For early primary hepatic carcinoma patients， CT-guided percutaneous MWA has better short-term and long-term efficacy， and lower adverse event rate.
[Key words] Percutaneous microwave ablation; Primary liver cancer; Adverse reactions; Malignant tumor; Liver cirrhosis
原發性肝癌是常见的恶性肿瘤疾病，有资料显示，我国新发肝癌患者以每年11万人数的速度增长，而流行病学调查结果表明肝癌疾病早期起病隐匿，多无特异性临床表现，且疾病发展速度快，大部分患者出现明显症状时已经进入中晚期[1]。我国大部分肝癌疾病是由肝硬化发展而来，患者普遍健康状态较差，病灶位于不同叶段，部分病灶位置可能靠近大血管等，部分原发性肝癌患者年龄较大，可能同时合并其它心脑血管疾病与糖尿病，诸多因素限制下导致患者错过最佳外科手术切除时机[2-3]。原发性肝癌疾病的临床表现包括肝区疼痛、乏力、腹胀、腹水、黄疸、恶病质表现，患病后会降低患者生存质量。本研究选取我院收治的86例早期原发性肝癌患者作为研究对象，分析CT引导经皮微波消融(MWA)的治疗效果，现报道如下。, 百拇医药(吴立刚 曾汉强)
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