孕妇IgG血型抗体效价与ABO新生儿溶血病关系的分析
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2011年1月15日
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【摘要】目的探讨孕妇IgG血型抗体效价与ABO新生儿溶血病发生率之间的关系。方法对716例妻子O型Rh阳性而丈夫非O型孕妇做IgG抗-A(B)效价测定, 对其中106例有HDN危险的孕妇所生新生儿做HDN血型血清学检查。结果716例O型孕妇中IgG抗-A(B)效价<64、64、128、256和≥512各组分别占609%、224%、109%、42%和17%。106例母婴血型不合且有ABO-HDN危险的孕妇所生新生儿中共有24例HDN阳性，占226%；孕妇IgG抗-A(B)效价为64、128、256和≥512各组HDN阳性率分别为120%、241%、381%和500%(P<001)。结论孕妇血清中IgG抗-A(B)效价高低与ABO-HDN的发生率成正相关，产前进行血清IgG抗体效价检测非常必要。【关键词】抗体效价 新生儿溶血病 抗-A(B)
Study of the relationship between blood group antibody IgG titer of pregnant women and ABO-HDNLI Yan-qiong.Zhumadian Central Hospital,Zhumadian 463000,China【Abstract】ObjectiveTo study the relationship between blood group antibody IgG titer of pregnant women and ABO hemolytic disease of newborn (HDN).MethodsBlood group antibody IgG titers of 716 pregnant women who were O and Rh positive with a non-O husband were detected. After born, blood groups,Coomb,s test,free antibody and antibody release test were done for those 106 babies who were in high risk of HDN.ResultsThe percent of anti-A(B) IgG titer<64 ......
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