蛋白磷酸酶PHLPP与PI3K/Akt信号通路的研究进展(4)
[13] 吴兴利，刘文静，杨丁友，等.胰岛素样生长因子-1对血管平滑肌细胞磷酸酶PHLPP蛋白表达的影响[J].实用医学杂志，2010，26(4)：552-554.
[14] Brognard J.PHLPP and a second isoform,PHLPP2,differentially attenuate the amplitude of Akt signaling by regulating distinct Akt isoforms[J].Mol Cell，2007，25：917-931.
[15] Brognard JE，Sierecki T，Gao,et al.PHLPP and a second isoform,PHLPP2,differentially attenuate the amplitude of Akt signaling by regulating distinct Akt isoforms[J].Mol Cell,2007,25(6):917-931.
[16] Gao,T.The phosphatase PHLPP controls the cellular levels of protein kinase C[J].Biol Chem，2008，283：6300-6311.
[17] Cozzone DS，Frojdo E，Disse,et al.Isoform-specific defects of insulin stimulation of Akt/protein kinase B (PKB) in skeletal muscle cells from type 2 diabetic patients[J].Diabetologia,2008,51(3):512-521.
[18] Choi JS,Park HJ,Kim HY,et al.Phosphorylation of PTEN and Akt in astrocytes of the rat hippocampus following transient forebrain ischemia[J].Cell Tissue Res,2005,319 (3):359-366.
[19] 吴兴利，杨丁友，颜伟，等.磷酸酶PHLPP1转基因对人脐静脉内皮细胞增殖的影响[J].南方医科大学学报,2010，30(6)：1298-1300.
(收稿日期：2011-10-12)
(本文编辑：陈丹云), http://www.100md.com(胡海峰 殷玥 马恒)
[14] Brognard J.PHLPP and a second isoform,PHLPP2,differentially attenuate the amplitude of Akt signaling by regulating distinct Akt isoforms[J].Mol Cell，2007，25：917-931.
[15] Brognard JE，Sierecki T，Gao,et al.PHLPP and a second isoform,PHLPP2,differentially attenuate the amplitude of Akt signaling by regulating distinct Akt isoforms[J].Mol Cell,2007,25(6):917-931.
[16] Gao,T.The phosphatase PHLPP controls the cellular levels of protein kinase C[J].Biol Chem，2008，283：6300-6311.
[17] Cozzone DS，Frojdo E，Disse,et al.Isoform-specific defects of insulin stimulation of Akt/protein kinase B (PKB) in skeletal muscle cells from type 2 diabetic patients[J].Diabetologia,2008,51(3):512-521.
[18] Choi JS,Park HJ,Kim HY,et al.Phosphorylation of PTEN and Akt in astrocytes of the rat hippocampus following transient forebrain ischemia[J].Cell Tissue Res,2005,319 (3):359-366.
[19] 吴兴利，杨丁友，颜伟，等.磷酸酶PHLPP1转基因对人脐静脉内皮细胞增殖的影响[J].南方医科大学学报,2010，30(6)：1298-1300.
(收稿日期：2011-10-12)
(本文编辑：陈丹云), http://www.100md.com(胡海峰 殷玥 马恒)