喹硫平治疗患者酒精依赖原理的探讨(1)
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【摘要】 目的 探讨喹硫平用于减轻患者酒精依赖的原理。方法 将74例酒依赖患者随机分为喹硫平组(37例)和对照组(37例),分别于治疗前及治疗后3、6、12个月,采用阳性与阴性症状量表(PANSS)、个人与社会功能量表(PSP)、治疗中出现的症状量表(TESS)作为评定指标。结果 对酒精依赖患者选用小剂量的喹硫平,能减少患者对酒精的依赖,降低复饮率。结论 喹硫平对酒依赖患者治疗有效的原理可能与DA、谷氨酸、GABA系统相关。
【关键词】 喹硫平; 酒精依赖; DA; 谷氨酸; GABA系统
The clinical observation of Quetiapine treat patients with alcohol dependence XU Qi-ling,ZHONG Yu-tao.The hulunbuir city mental health center,Yakeshi 022150,China
【Abstract】 Objective To study the quetiapine used to relieve patie -nts the principle of alcohol dependence.Methods 74 patients of alcohol dependence were randomly divided into quetiapine group (37 cases) and matched group (37 cases), respectively, in before and after treatment for three, six, Twelve months, with the positive and negative symptoms scale (PANSS), personal and social function scale (PSP), appearing in the treatment emergent symptoms scale (TESS) as evaluation index ......
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