难治性癫痫患者脑内HIF—1α与多药耐药基因1表达的相关性及其意义(3)
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参见附件。
[4]谷文龙.HIF-1α、P-gp、COX-2在非小细胞肺癌中的表达及临床意义[D].宁夏医科大学,2010.
[5] Villanueva V,Giron J M,Martin J,et al.Quality of life and economic impact of refractory epilepsy in Spain:the ESPERA study[J].Neurologia,2013,28(4):195-204.
[6] Ban J J,Jung K H,Chu K,et al.Profiles of multidrug resistance protein-1 in the peripheral blood mononuclear cells of patients with refractory epilepsy[J].PLoS One,2012,7(5):e36985.
[7] Mandl M,Kapeller B,Lieber R,et al.Hypoxia-inducible factor-1β(HIF-1β) is upregulated in a HIF-1α-dependent manner in 518A2 human melanoma cells under hypoxic conditions[J].Biochem Biophys Res Commun,2013,434(1):166-172.
[8] Corcoran A,O'Connor J J.Hypoxia-inducible factor signalling mechanisms in the central nervous system[J].Acta Physiol (Oxf),2013,208(4):298-310.
[9] Wartenberg M,Gronczynska S,Bekhite M M,et al.Regulation of the multidrug resistance transporter P-glycoprotein in multicellular prostate tumor spheroids by hyperthermia and reactive oxygen species[J].Int J Cancer,2005,113(2):229-240.
[10] Comerford K M,Cummins E P,Taylor C T.c-Jun NH2-terminal kinase activation contributes to hypoxia-inducible factor 1α-dependent P-glycoprotein expression in hypoxia[J].Cancer Res,2004,64(24):9057-9061.
[11] Comerford K M,Wallace T J,Karhausen J,et al.Hypoxia-inducible factor-1-dependent regulation of the multidrug resistance (MDR1) gene[J].Cancer Res,2002,62(12):3387-3394.
(收稿日期:2013-12-16) (本文编辑:欧丽)
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