甘精胰岛素联合吡格列酮治疗磺脲类继发失效2型糖尿病疗效观察(1)
【摘要】 目的：探讨甘精胰岛素联合吡格列酮治疗磺脲类继发性失效的2型糖尿病的疗效。方法：60例患者随机数字表法分为A组和B组各30例；A组给予甘精胰岛素联合吡格列酮治疗，B组给予门冬胰岛素30R皮下注射，两组均治疗12周。测定治疗前后空腹血糖(FBG)、餐后2 h血糖(2 h PG)、糖化血红蛋白(HbA1c)、空腹C肽(FCP)、餐后2 h C肽(2 h CP)及低血糖发生率。结果：治疗12周后，两组FBG、2 h PG和HbA1c均明显下降，FCP和2hCP均明显升高，与治疗前比较差异有统计学意义(P0.05). The low blood glucose reaction was noticed in 1 case (3.3%) in group A， but 7 cases (23.3%)in group B， and the differences were statistically significant (PO.05)，具有可比性。, http://www.100md.com(李翔)