尿常规检验与C—反应蛋白诊断小儿急性阑尾炎的临床价值(1)
【摘要】 目的:比较尿常规检验和C-反应蛋白在小儿急性阑尾炎诊断中的应用价值。方法:选取本院收治的250例小儿急性阑尾炎患者作为研究对象,本组患者术前均进行C-反应蛋白检验及尿常规检验,比较两种检验方法的阑尾炎检出率及诊断敏感度。结果:CRP的阳性检出率显著高于尿常规检验,检验平均用时明显长于尿常规检验(P<0.05);CRP对单纯性阑尾炎的阳性检出率显著高于尿常规(P<0.05),对化脓性阑尾炎和坏疽穿孔性阑尾炎的阳性检出率与对照组比较差异无统计学意义。结论:与尿常规检验相比,C-反应蛋白对小儿急性阑尾炎的检出率更高,诊断敏感性更好,但其检测过程相对繁琐,耗时较长,临床上应根据实际情况合理选择检测项目。
【关键词】 小儿急性阑尾炎; C-反应蛋白; 尿常规
Clinical Value of Urine Routine Test and C-reactive Protein in Diagnosis of Acute Appendicitis in Children/WEI Bing-hua,CHI Qiao-zhen.//Medical Innovation of China,2015,12(16):124-125
, 百拇医药
【Abstract】 Objective:To compare the urine test and C-reactive protein value in the diagnosis of acute appendicitis in children.Method:250 cases in our hospital with acute appendicitis in children as research subjects underwent preoperative CRP test and urine test,the detection rate of appendicitis was compared for the two testing methods and diagnostic sensitivity.Result:CRP positive rate was significantly higher than the urine test,urine test was significantly longer than the average time of test (P<0.05).CRP for simple appendicitis positive rate was significantly higher than that of urine (P<0.05),purulent gangrenous appendicitis and perforated appendicitis positive rate compared with control group had no significant difference.Conclusion:CRP in children with acute appendicitis higher detection rate than urine testing,diagnostic sensitivity is better,but the detection process is relatively cumbersome,the time-consuming is relatively long,should be choose a reasonable test method based on the actual clinical situation.
, 百拇医药
【Key words】 Acute appendicitis in children; C-reactive protein; Urine
First-author’s address:Longgang Nanwan People’s Hospital,Shenzhen 518123,China
doi:10.3969/j.issn.1674-4985.2015.16.045
急性阑尾炎是临床常见的小儿急腹症,且容易并发阑尾穿孔和弥漫性腹膜炎[1]。由于儿童的语言表达能力欠佳,临床上容易出现误诊,进而影响治疗效果。目前,C-反应蛋白(CRP和尿常规检验都是临床诊断阑尾炎的常用手段,本研究旨在比较这两种方法诊断小儿急性阑尾炎的准确性,现报道如下。
1 资料与方法
, 百拇医药
1.1 一般资料 选取本院2013年5月-2014年5月收治的250例小儿急性阑尾炎患者作为研究对象,所有患儿术后经病理检查均明确诊断为急性阑尾炎。男128例,女122例,年龄3~13岁,平均(9.8±2.4)岁,病程5~22 h,平均(13.5±3.8)h。疾病类型:单纯性阑尾炎168例,坏疽性阑尾炎10例,化脓性阑尾炎72例。排除合并肝肾功能异常者,合并可影响研究结果的其他疾病者。本组患儿术前均进行C-反应蛋白和尿常规检验。
1.2 方法
1.2.1 尿常规检验 患儿入院后,取20 mL中段尿液制成尿液标本,留样30 min后送检。检验内容包括尿糖定性、白细胞、蛋白质、管型、上皮细胞、红细胞、酸碱度、透明度、颜色等。尿液颜色呈淡黄色、透明状为正常;尿液pH在4.5~8.0范围内为正常;尿液比重在1.015~1.025之间为正常;红细胞、白细胞均以不超过3个为正常;尿蛋白、尿糖分别以不超过80 mg、900 mg为正常;管型、尿亚硝酸盐、尿胆原和胆红素、隐血、酮体结果均以阴性为正常。
1.2.2 CRP检验 抽取患儿的静脉外周血3 mL,先进行白细胞数检测,再进行离心、分离上层血清,应用免疫散射比浊法进行CRP检测,CRP值≤8 mg/L为阴性。, 百拇医药(魏炳华 池巧珍)
【关键词】 小儿急性阑尾炎; C-反应蛋白; 尿常规
Clinical Value of Urine Routine Test and C-reactive Protein in Diagnosis of Acute Appendicitis in Children/WEI Bing-hua,CHI Qiao-zhen.//Medical Innovation of China,2015,12(16):124-125
, 百拇医药
【Abstract】 Objective:To compare the urine test and C-reactive protein value in the diagnosis of acute appendicitis in children.Method:250 cases in our hospital with acute appendicitis in children as research subjects underwent preoperative CRP test and urine test,the detection rate of appendicitis was compared for the two testing methods and diagnostic sensitivity.Result:CRP positive rate was significantly higher than the urine test,urine test was significantly longer than the average time of test (P<0.05).CRP for simple appendicitis positive rate was significantly higher than that of urine (P<0.05),purulent gangrenous appendicitis and perforated appendicitis positive rate compared with control group had no significant difference.Conclusion:CRP in children with acute appendicitis higher detection rate than urine testing,diagnostic sensitivity is better,but the detection process is relatively cumbersome,the time-consuming is relatively long,should be choose a reasonable test method based on the actual clinical situation.
, 百拇医药
【Key words】 Acute appendicitis in children; C-reactive protein; Urine
First-author’s address:Longgang Nanwan People’s Hospital,Shenzhen 518123,China
doi:10.3969/j.issn.1674-4985.2015.16.045
急性阑尾炎是临床常见的小儿急腹症,且容易并发阑尾穿孔和弥漫性腹膜炎[1]。由于儿童的语言表达能力欠佳,临床上容易出现误诊,进而影响治疗效果。目前,C-反应蛋白(CRP和尿常规检验都是临床诊断阑尾炎的常用手段,本研究旨在比较这两种方法诊断小儿急性阑尾炎的准确性,现报道如下。
1 资料与方法
, 百拇医药
1.1 一般资料 选取本院2013年5月-2014年5月收治的250例小儿急性阑尾炎患者作为研究对象,所有患儿术后经病理检查均明确诊断为急性阑尾炎。男128例,女122例,年龄3~13岁,平均(9.8±2.4)岁,病程5~22 h,平均(13.5±3.8)h。疾病类型:单纯性阑尾炎168例,坏疽性阑尾炎10例,化脓性阑尾炎72例。排除合并肝肾功能异常者,合并可影响研究结果的其他疾病者。本组患儿术前均进行C-反应蛋白和尿常规检验。
1.2 方法
1.2.1 尿常规检验 患儿入院后,取20 mL中段尿液制成尿液标本,留样30 min后送检。检验内容包括尿糖定性、白细胞、蛋白质、管型、上皮细胞、红细胞、酸碱度、透明度、颜色等。尿液颜色呈淡黄色、透明状为正常;尿液pH在4.5~8.0范围内为正常;尿液比重在1.015~1.025之间为正常;红细胞、白细胞均以不超过3个为正常;尿蛋白、尿糖分别以不超过80 mg、900 mg为正常;管型、尿亚硝酸盐、尿胆原和胆红素、隐血、酮体结果均以阴性为正常。
1.2.2 CRP检验 抽取患儿的静脉外周血3 mL,先进行白细胞数检测,再进行离心、分离上层血清,应用免疫散射比浊法进行CRP检测,CRP值≤8 mg/L为阴性。, 百拇医药(魏炳华 池巧珍)