110例围生期高危因素与脐血血气分析对新生儿预后的预测价值(1)
【摘要】 目的：探讨围生期高危因素与脐血血气分析对新生儿预后的预测价值。方法：选取2012年10月-2014年8月本院产科的产妇中胎儿窘迫者110例，根据胎儿窘迫病因将患者分为：A组(单纯胎心监护异常)40例，B组(单纯羊水污染)39例，C组(胎心监护异常合并羊水污染)31例，同期选取正常新生儿50例作为对照组(D组)，全部研究对象均检测脐血血气。结果：A组、B组、C组产妇妊娠期糖尿病和妊娠期高血压发生率均显著高于D组，产妇娩出肺炎新生儿、呼吸窘迫综合征新生儿和缺血缺氧性脑病新生儿比例均显著高于D组，A组、B组、C组新生儿Apgar评分≤7分所占比例高于D组，新生儿Apgar评分>7分所占比例均低于D组，组间比较差异有统计学意义(P<0.05) ；脐血血气正常新生儿围生期患病率显著低于脐血血气异常新生儿(P<0.05)。结论：合并围生期高危因素(胎儿窘迫)产妇娩出新生儿窒息及其疾病患病率显著增高，脐血综合分析异常者新生儿患病率亦显著增高，新生儿预后状况越差，围生期高危因素与脐血综合分析对新生儿预后具有重要的预测价值。
【关键词】 围生期； 脐血血气； 新生儿； 预后
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【Abstract】 Objective：To evaluate the predictive value of risk factors and a comprehensive analysis of umbilical cord blood of newborns with perinatal outcomes.Method：110 cases of fetal distress in maternal obstetric hospital from October 2012 to August 2014 were selected，according to the etiology of fetal distress were divided into：group A (abnormal fetal heart rate monitoring alone) 40 cases，group B (simple meconium) 39 cases，group C (abnormal fetal heart rate monitoring merger meconium) 31 cases，50 cases of normal newborn period were selected as a control group (group D)，all subjects were detected in umbilical cord blood.Result：A，B，C maternal gestational diabetes and gestational hypertension were significantly higher in group D，maternal newborn delivered pneumonia，respiratory distress syndrome，neonatal and neonatal hypoxic-ischemic encephalopathy significant proportion higher than the D group，group A， group B and group C had a significantly higher proportion of neonatal Apgar score 7 or less branch office group D， neonatal Apgar score were significantly lower than that of group D percentage > 7 branch office， compared the difference between groups was statistically significant(P<0.05)，umbilical cord blood normal newborn blood perinatal morbidity was significantly lower than the abnormal newborn umbilical cord blood (P<0.05).Conclusion：The combined perinatal risk factors (fetal distress) were maternal and neonatal asphyxia delivered significantly higher prevalence of the disease，a comprehensive analysis of umbilical cord abnormalities in neonatal morbidity was also significantly increased，the worse the prognosis for the newborn，Wai Health risk factors and comprehensive analysis of umbilical cord blood has an important predictive value of neonatal outcomes.
【Key words】 Perinatal period； Integrated cord blood gas； Newborns； Prognosis
First-author’s address：The Third People’s Hospital of Shaoguan，Shaoguan 512122，China
doi：10.3969/j.issn.1674-4985.2015.17.003, 百拇医药(谭建萍等)
【关键词】 围生期； 脐血血气； 新生儿； 预后
, http://www.100md.com
【Abstract】 Objective：To evaluate the predictive value of risk factors and a comprehensive analysis of umbilical cord blood of newborns with perinatal outcomes.Method：110 cases of fetal distress in maternal obstetric hospital from October 2012 to August 2014 were selected，according to the etiology of fetal distress were divided into：group A (abnormal fetal heart rate monitoring alone) 40 cases，group B (simple meconium) 39 cases，group C (abnormal fetal heart rate monitoring merger meconium) 31 cases，50 cases of normal newborn period were selected as a control group (group D)，all subjects were detected in umbilical cord blood.Result：A，B，C maternal gestational diabetes and gestational hypertension were significantly higher in group D，maternal newborn delivered pneumonia，respiratory distress syndrome，neonatal and neonatal hypoxic-ischemic encephalopathy significant proportion higher than the D group，group A， group B and group C had a significantly higher proportion of neonatal Apgar score 7 or less branch office group D， neonatal Apgar score were significantly lower than that of group D percentage > 7 branch office， compared the difference between groups was statistically significant(P<0.05)，umbilical cord blood normal newborn blood perinatal morbidity was significantly lower than the abnormal newborn umbilical cord blood (P<0.05).Conclusion：The combined perinatal risk factors (fetal distress) were maternal and neonatal asphyxia delivered significantly higher prevalence of the disease，a comprehensive analysis of umbilical cord abnormalities in neonatal morbidity was also significantly increased，the worse the prognosis for the newborn，Wai Health risk factors and comprehensive analysis of umbilical cord blood has an important predictive value of neonatal outcomes.
【Key words】 Perinatal period； Integrated cord blood gas； Newborns； Prognosis
First-author’s address：The Third People’s Hospital of Shaoguan，Shaoguan 512122，China
doi：10.3969/j.issn.1674-4985.2015.17.003, 百拇医药(谭建萍等)