难治性高血压合并阻塞性睡眠呼吸暂停低通气综合征治疗的临床分析(1)
【摘要】 目的：研究难治性高血压合并阻塞性睡眠呼吸暂停低通气综合征(OSAHS)的治疗方法与临床疗效。方法：选取2011年1月-2014年12月本院收治的61例难治性高血压合并阻塞性睡眠呼吸暂停低通气综合征患者，按照随机数字表法将其分为对照组30例和观察组31例。对照组在血压测量、多导睡眠图监测(PSG)基础上给予常规药物治疗，观察组则增加手术或持续气道正压通气(CPAP)相配合进行治疗。观察比较两组患者的治疗效果、血压治疗达标率及治疗前后的血压和心率。结果：经治疗后，观察组患者临床治疗总有效率90.32%(28/31)明显高于对照组的63.33%(19/30)，比较差异有统计学意义( 字2=6.2801，P<0.05)。两组患者治疗前SBP、DBP与心率均无显著差异(P>0.05)，而两组患者治疗后的SBP、DBP与心率均有所改善(P<0.05)，而观察组治疗后的SBP、DBP与心率改善情况均显著优于对照组(P<0.05)。观察组患者血压治疗达标率77.42%明显高于对照组的33.33%，差异有统计学意义(P<0.05)。结论：在难治性高血压合并OSAHS患者治疗中，可通过CPAP有效治疗OSAHS、改善患者睡眠质量、呼吸障碍与低氧血症来降低血压，从而治疗难治性高血压，以提高治疗效果。
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【关键词】 难治性高血压； 阻塞性睡眠呼吸暂停低通气综合征； 临床分析
Clinical Analysis of Refractory Hypertensive Patients with Obstructive Sleep Apnea-hypopnea Syndrome Treatment/ZOU Bin，ZOU Rong.//Medical Innovation of China，2015，12(20)：059-061
【Abstract】 Objective：To study the treatment method and clinical curative effect of resistant hypertension combined OSAHS method.Method：61 refractory hypertension patients with obstructive sleep apnea-hypopnea syndrome admitted to our hospital from January 2011 to December 2014 were selected as research objects，they were divided into the control group for 30 cases and the observation group for 31 cases according to the random number table method.The control group was treated with conventional drug therapy on the basis of blood pressure measurement and polysomnography(PSG) monitoring，the observation group was treated with the combination of surgical or continuous positive airway pressure (CPAP).The clinical effect，compliance rate of blood pressure treatment，blood pressure and heart rate before and after treatment between the two groups were observed and compared.Result：After treatment，the clinical total effective rate of the observation group was 90.32%(28/31)，which was significantly higher than 63.33%(19/30)of the control group，the difference was statistically significant( 字2=6.2801，P<0.05).There were no statistically significant differences in SBP，DBP and heart rate before treatment between the two groups(P>0.05)，the SBP，DBP and heart rate after treatment of the two groups were all improved，the improvement of SBP，DBP and heart rate after treatment in the observation group were significantly better than the control group(P<0.05).The compliance rate of blood pressure treatment in the observation group was 77.42%，which was significantly higher than 33.33% in the control group，the difference was statistically significant(P<0.05).Conclusion：In patients with refractory hypertension merger OSAHS treatment，can treat OSAHS effectively by CPAP，improve sleep quality，respiratory disorders and hypoxemia to lower blood pressure，and thus the treatment of refractory hypertension，in order to improve the therapeutic effect., 百拇医药(邹斌 邹容)
, http://www.100md.com
【关键词】 难治性高血压； 阻塞性睡眠呼吸暂停低通气综合征； 临床分析
Clinical Analysis of Refractory Hypertensive Patients with Obstructive Sleep Apnea-hypopnea Syndrome Treatment/ZOU Bin，ZOU Rong.//Medical Innovation of China，2015，12(20)：059-061
【Abstract】 Objective：To study the treatment method and clinical curative effect of resistant hypertension combined OSAHS method.Method：61 refractory hypertension patients with obstructive sleep apnea-hypopnea syndrome admitted to our hospital from January 2011 to December 2014 were selected as research objects，they were divided into the control group for 30 cases and the observation group for 31 cases according to the random number table method.The control group was treated with conventional drug therapy on the basis of blood pressure measurement and polysomnography(PSG) monitoring，the observation group was treated with the combination of surgical or continuous positive airway pressure (CPAP).The clinical effect，compliance rate of blood pressure treatment，blood pressure and heart rate before and after treatment between the two groups were observed and compared.Result：After treatment，the clinical total effective rate of the observation group was 90.32%(28/31)，which was significantly higher than 63.33%(19/30)of the control group，the difference was statistically significant( 字2=6.2801，P<0.05).There were no statistically significant differences in SBP，DBP and heart rate before treatment between the two groups(P>0.05)，the SBP，DBP and heart rate after treatment of the two groups were all improved，the improvement of SBP，DBP and heart rate after treatment in the observation group were significantly better than the control group(P<0.05).The compliance rate of blood pressure treatment in the observation group was 77.42%，which was significantly higher than 33.33% in the control group，the difference was statistically significant(P<0.05).Conclusion：In patients with refractory hypertension merger OSAHS treatment，can treat OSAHS effectively by CPAP，improve sleep quality，respiratory disorders and hypoxemia to lower blood pressure，and thus the treatment of refractory hypertension，in order to improve the therapeutic effect., 百拇医药(邹斌 邹容)