颅内静脉和静脉窦血栓形成32例的临床和影像分析(1)
【摘要】 目的:探讨颅内静脉和静脉窦血栓形成(CVST)的可能病因、临床表现、影像学特征。方法:回顾性分析2009年10月-2014年10月新疆自治区人民医院神经内科收治的32例CVST患者临床资料。32例患者均在急性/亚急性期行磁共振成像(MRI)和磁共振静脉成像(MRV)检查。结果:32例患者年龄20~54岁,平均(35±8.4)岁,女22例(68.8%)。病因未明20例(62.5%),发生于产褥期8例(25.0%),合并中耳炎3例(9.4%),口服避孕药1例(3.1%)。临床表现首发症状为头痛29例(90.6%),视力下降10例(31.3%),局灶性神经功能缺损症状9例(28.1%),痫性发作7例(21.9%),意识障碍6例(18.7%),复视1例(3.1%)。病变累及上矢状窦23例(71.9%),横窦25例(78.1%),乙状窦17例(53.1%),直窦9例(28.1%),皮层静脉2例(6.3%),下矢状窦1例(3.1%)。结论:CVST临床表现复杂多变,缺少特异性,MRI与MRV结合是目前主要的确诊CSVT的方法。
, 百拇医药 【关键词】 颅内静脉和静脉窦血栓形成; 临床特点; 影像学特点
【Abstract】 Objective:To investigate the possible cause, clinical symptoms and imaging characteristics of cerebral vein and sinus thrombosis (CVST).Method:The clinical data of 32 patients with CVST admitted from Octomber 2009 to Octomber 2014 in the department of neurology People’s Hospital of Xinjiang Uygur Autonomous Region were analyzed retrospectively. Magnetic resonance imaging (MRI) and magnetic resonance venography (MRV) were performed in all 32 patients in acute/subacute period.Result:In the 32 cases,22 cases (68.8%)were female,the age ranged from 20 to 54 years,the average were(35±8.4)years. No underlying risk factor was found of 20 cases (62.5%),there were 8 cases(25.0%)in puerperium, 3 cases (9.4%)in otitis media and 1 case (3.1%)of taking pill.29 cases (90.6%) of headache,10 cases(31.3%)of decreased vision,9 cases (28.1%) of focal neurological syndrome,7 cases(21.9%)of epileptic seizures,6 cases (18.7%) of conscious disturbance and 1 case (3.1%)of diplopia. 23 cases (71.9%)of superior sagittal sinus,25 cases(78.1%)of transverse sinus,17 cases (53.1%) of sigmoid sinus,9 cases (28.1%) of straight sinus, 2 cases (6.3%)of cortical veins and 1 cases (3.1%)of inferior sagittal sinus.Conclusion:The clinical manifestations of CVST are complicated and nonspecific.MRI combined with MRV is currently a major method to confirm the diagnosis of CVST.
, 百拇医药
【Key words】 Cerebral vein sinus thrombosis; Clinical feature; Imaging characteristics
颅内静脉和静脉窦血栓形成(Cerebral vein and sinus thrombosis,CVST),是指由多种病因引起的以脑静脉回流受阻,常伴有脑脊液吸收障碍导致颅内高压为特征的特殊类型脑血管病。CVST相对少见,年发病率大约为0.5/10万,占所有卒中的0.5%~1%[1]。多见于孕妇、服用口服避孕药的女性以及<45岁的年轻人群[2]。由于CVST的临床表现变化多样,诊断较困难,总死亡率为15%[3]。在我国,误诊、漏诊和诊断延误非常常见,具有较高的病残率和病死率[2]。近来,随着影像学技术的发展与普及,CVST的早期诊断率明显提高,病死率也逐渐下降。本文对新疆维吾尔自治区人民医院神经内科收治的32例CVST患者可能的病因、临床特点、影像学特征进行分析,以期提高对CVST的临床诊治水平。
1 资料与方法
1.1 一般资料 回顾性分析新疆维吾尔自治区人民医院神经内科2009年10月-2014年10月年连续收治的CVST患者32例。纳入标准:明确诊断为CVST,本院神经内科住院,回顾患者病例及影像学资料,确诊需要辅助检查中磁共振成像(Magnetic resonance imaging,MRI)联合磁共振静脉成像(Magnetic resonance venography,MRV)中至少一项符合CVST的影像特点[4]。排除标准:诊断尚不能明确的患者。, http://www.100md.com(李勍等)
, 百拇医药 【关键词】 颅内静脉和静脉窦血栓形成; 临床特点; 影像学特点
【Abstract】 Objective:To investigate the possible cause, clinical symptoms and imaging characteristics of cerebral vein and sinus thrombosis (CVST).Method:The clinical data of 32 patients with CVST admitted from Octomber 2009 to Octomber 2014 in the department of neurology People’s Hospital of Xinjiang Uygur Autonomous Region were analyzed retrospectively. Magnetic resonance imaging (MRI) and magnetic resonance venography (MRV) were performed in all 32 patients in acute/subacute period.Result:In the 32 cases,22 cases (68.8%)were female,the age ranged from 20 to 54 years,the average were(35±8.4)years. No underlying risk factor was found of 20 cases (62.5%),there were 8 cases(25.0%)in puerperium, 3 cases (9.4%)in otitis media and 1 case (3.1%)of taking pill.29 cases (90.6%) of headache,10 cases(31.3%)of decreased vision,9 cases (28.1%) of focal neurological syndrome,7 cases(21.9%)of epileptic seizures,6 cases (18.7%) of conscious disturbance and 1 case (3.1%)of diplopia. 23 cases (71.9%)of superior sagittal sinus,25 cases(78.1%)of transverse sinus,17 cases (53.1%) of sigmoid sinus,9 cases (28.1%) of straight sinus, 2 cases (6.3%)of cortical veins and 1 cases (3.1%)of inferior sagittal sinus.Conclusion:The clinical manifestations of CVST are complicated and nonspecific.MRI combined with MRV is currently a major method to confirm the diagnosis of CVST.
, 百拇医药
【Key words】 Cerebral vein sinus thrombosis; Clinical feature; Imaging characteristics
颅内静脉和静脉窦血栓形成(Cerebral vein and sinus thrombosis,CVST),是指由多种病因引起的以脑静脉回流受阻,常伴有脑脊液吸收障碍导致颅内高压为特征的特殊类型脑血管病。CVST相对少见,年发病率大约为0.5/10万,占所有卒中的0.5%~1%[1]。多见于孕妇、服用口服避孕药的女性以及<45岁的年轻人群[2]。由于CVST的临床表现变化多样,诊断较困难,总死亡率为15%[3]。在我国,误诊、漏诊和诊断延误非常常见,具有较高的病残率和病死率[2]。近来,随着影像学技术的发展与普及,CVST的早期诊断率明显提高,病死率也逐渐下降。本文对新疆维吾尔自治区人民医院神经内科收治的32例CVST患者可能的病因、临床特点、影像学特征进行分析,以期提高对CVST的临床诊治水平。
1 资料与方法
1.1 一般资料 回顾性分析新疆维吾尔自治区人民医院神经内科2009年10月-2014年10月年连续收治的CVST患者32例。纳入标准:明确诊断为CVST,本院神经内科住院,回顾患者病例及影像学资料,确诊需要辅助检查中磁共振成像(Magnetic resonance imaging,MRI)联合磁共振静脉成像(Magnetic resonance venography,MRV)中至少一项符合CVST的影像特点[4]。排除标准:诊断尚不能明确的患者。, http://www.100md.com(李勍等)