复方丹参注射液和50%硫酸镁溶液湿敷在新生儿输液外渗中的效果对比(1)
【摘要】 目的：观察比较复方丹参注射液和50%硫酸镁溶液湿敷治疗新生儿输液外渗的临床效果。方法：选取2011年9月-2014年7月于本院行静脉输液的新生儿共131例，均有输液外渗症状，随机分为对照组65例和观察组66例，对照组湿敷50%硫酸镁溶液治疗，观察组湿敷复方丹参注射液治疗，比较两组的消肿时间、显效时间、治疗效果及不良反应。结果：观察组的开始消肿、完全消肿、显效时间分别为(2.78±0.57)h、(9.12±1.13)h和(5.73±0.63)h，而对照组分别为(5.61±1.49)h、(16.32±1.43)h和(10.54±1.05)h，观察组时间均短于对照组，两组比较差异均有统计学意义(P<0.05)；观察组和对照组治疗总有效率分别为98.48%和73.85%，观察组高于对照组，两组比较差异有统计学意义(P<0.05)；观察组未出现明显不良反应，而对照组发生率为12.31%，观察组不良反应发生情况明显优于对照组，差异有统计学意义(P<0.05)。结论：对临床中出现输液外渗的新生儿应用复方丹参注射液湿敷，起效快，效果好，安全性高，值得推广。
, 百拇医药
【关键词】 输液外渗； 新生儿； 复方丹参注射液； 50%硫酸镁溶液； 湿敷
【Abstract】 Objective：To observe and compare the clinical effect of compound Danshen injection and 50% Magnesium sulfate solution wet packing in treatment of neonatal transfusion exosmose. Method：131 newborn with intravenous infusion in our hospital were chosen from September 2011 to July 2014.All patients had symptoms of infusion extravasation and were randomly divided into the control group of 65 cases and the observation group of 66 cases.The control group was given 50% magnesium sulfate wet solution treatment，while the observation group was treated by compound Danshen injection.The swelling time， onset time， the therapeutic effect and adverse reaction of two groups were compared. Result：The start swelling time，the complete detumescence time and the effective time of observation group were respectively (2.78±0.57)h，(9.12±1.13)h and (5.73±0.63)h，while those time in the control group were respectively (5.61±1.49)h，(16.32±1.43)h and (10.54±1.05)h，the observation group were shorter than those of the control group ，the differences were statistically significance(P<0.05).The total effective rate of the observation group and the control group were respectively 98.48% and 73.85%，the observation group was higher than that of control group，the difference was statistically significance(P<0.05).The observation group had no obvious adverse reaction，while the occurrence of adverse reactions in the control group was 12.31%，the observation group was significantly better than the control group ，the difference was statistically significance(P<0.05).Conclusion：Neonatal transfusion exosmosis with compound Danshen injection has fast acting，good effect and high safety，it is worth popularization.
【Key words】 Transfusion exosmosis； Newborn； Compound Danshen injection； 50% Magnesium sulfate solution； Wet compress
First-author’s address：People’s Hospital of Heping County，Heping 517200，China
doi：10.3969/j.issn.1674-4985.2015.28.044, http://www.100md.com(袁玉环等)
, 百拇医药
【关键词】 输液外渗； 新生儿； 复方丹参注射液； 50%硫酸镁溶液； 湿敷
【Abstract】 Objective：To observe and compare the clinical effect of compound Danshen injection and 50% Magnesium sulfate solution wet packing in treatment of neonatal transfusion exosmose. Method：131 newborn with intravenous infusion in our hospital were chosen from September 2011 to July 2014.All patients had symptoms of infusion extravasation and were randomly divided into the control group of 65 cases and the observation group of 66 cases.The control group was given 50% magnesium sulfate wet solution treatment，while the observation group was treated by compound Danshen injection.The swelling time， onset time， the therapeutic effect and adverse reaction of two groups were compared. Result：The start swelling time，the complete detumescence time and the effective time of observation group were respectively (2.78±0.57)h，(9.12±1.13)h and (5.73±0.63)h，while those time in the control group were respectively (5.61±1.49)h，(16.32±1.43)h and (10.54±1.05)h，the observation group were shorter than those of the control group ，the differences were statistically significance(P<0.05).The total effective rate of the observation group and the control group were respectively 98.48% and 73.85%，the observation group was higher than that of control group，the difference was statistically significance(P<0.05).The observation group had no obvious adverse reaction，while the occurrence of adverse reactions in the control group was 12.31%，the observation group was significantly better than the control group ，the difference was statistically significance(P<0.05).Conclusion：Neonatal transfusion exosmosis with compound Danshen injection has fast acting，good effect and high safety，it is worth popularization.
【Key words】 Transfusion exosmosis； Newborn； Compound Danshen injection； 50% Magnesium sulfate solution； Wet compress
First-author’s address：People’s Hospital of Heping County，Heping 517200，China
doi：10.3969/j.issn.1674-4985.2015.28.044, http://www.100md.com(袁玉环等)