米非司酮及甲氨蝶呤联合宫外孕Ⅱ号方加减治疗输卵管妊娠的临床分析(1)
【摘要】 目的：分析和研究米非司酮及甲氨蝶呤联合宫外孕Ⅱ号方加减治疗输卵管妊娠的临床疗效。方法：选取2013年4月-2015年2月本院收治的输卵管妊娠患者58例，按照随机数字表法将其分为观察组和对照组，每组各29例。对照组患者给予米非司酮+甲氨喋呤治疗，观察组患者在对照组治疗基础上加用宫外孕Ⅱ号方加减治疗，观察比较两组患者的治疗效果。结果：经治疗后，观察组的治疗总有效率93.1%明显高于对照组的69.0%，β-hCG水平值下降时间、盆腔积液吸收时间、包块吸收时间均明显短于对照组，差异均有统计学意义(P<0.05)。两组患者用药期间不良反应发生率比较差异无统计学意义( 字2=0.38，P>0.05)。结论：将宫外孕Ⅱ号方加减与米非司酮、甲氨蝶呤联合应用于输卵管妊娠患者治疗中，能够达到快速杀灭妊娠组织并促进其吸收的目的，对提高治疗效果及减轻患者痛苦均具有重要作用。
【关键词】 输卵管妊娠； 米非司酮； 甲氨喋呤； 宫外孕Ⅱ号方
【Abstract】 Objective：To analyze and research the clinical effect of Mifepristone and Methotrexate united plus minus Recipe Ⅱ for Ectopic Pregnancy in the treatment of tubal pregnancy.Method：58 patients with tubal pregnancy admitted to our hospital from April 2013 to February 2015 were selected and divided into the observation group and the control group according to the random number table method，29 cases in each group.The control group was treated with Mifepristone and Methotrexate，the observation group was treated with plus minus Recipe Ⅱ for Ectopic Pregnancy on the basis of the control group，the therapeutic effect of the two groups were observed and compared.Result：After treatment，the total effective rate of the observation group was 93.1%，which was significantly higher than 69.0% of the control group，the β-hCG level values fall time，pelvic effusion absorption time and the mass absorption time of the observation group were significantly shorter than those of the control group， the differences were statistically significant(P<0.05).There was no statistically significant difference in the adverse drug reactions during the treatment between the two groups( 字2=0.38，P>0.05).Conclusion：The plus minus Recipe Ⅱ for Ectopic Pregnancy united Mifepristone and Methotrexate(MTX) application in the treatment of tubal pregnancy，can achieve the purpose of quickly kill the pregnancy tissue and promote the absorption，has the important function of improving the treatment effect and reducing the pain of patients.
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【Key words】 Tubal pregnancy； Mifepristone； Methotrexate； The decoction of ectopic pregnancy Ⅱ
First-author’s address：The People’s Hospital of Yongfeng County，Yongfeng 331500，China
doi：10.3969/j.issn.1674-4985.2015.32.033
异位妊娠在妇产科临床上是较常见疾病类型，其包括输卵管妊娠、腹腔妊娠、卵巢妊娠、间质部妊娠等[1-3]。其中输卵管妊娠发病率较高，据相关文献[4-5]报道，输卵管妊娠患者数量约占异位妊娠患者总数的95%左右。其多由输卵病变致管腔闭塞或狭窄，阻碍孕卵正常运行，使其在管腔内着床所致。患者临床症状主要表现为下腹单侧酸坠感或隐痛、停经、阴道不规则出血等，若输卵管妊娠破裂，可引发患者出现休克、晕厥、急性大出血等，从而危及患者生命安全[6]。为了探讨保守治疗输卵管妊娠有效途径，本文选取输卵管妊娠患者29例，在米非司酮联合甲氨喋呤治疗基础上加用宫外孕Ⅱ号方加减治疗，疗效颇为明显，现报告如下：, 百拇医药(彭春华)
【关键词】 输卵管妊娠； 米非司酮； 甲氨喋呤； 宫外孕Ⅱ号方
【Abstract】 Objective：To analyze and research the clinical effect of Mifepristone and Methotrexate united plus minus Recipe Ⅱ for Ectopic Pregnancy in the treatment of tubal pregnancy.Method：58 patients with tubal pregnancy admitted to our hospital from April 2013 to February 2015 were selected and divided into the observation group and the control group according to the random number table method，29 cases in each group.The control group was treated with Mifepristone and Methotrexate，the observation group was treated with plus minus Recipe Ⅱ for Ectopic Pregnancy on the basis of the control group，the therapeutic effect of the two groups were observed and compared.Result：After treatment，the total effective rate of the observation group was 93.1%，which was significantly higher than 69.0% of the control group，the β-hCG level values fall time，pelvic effusion absorption time and the mass absorption time of the observation group were significantly shorter than those of the control group， the differences were statistically significant(P<0.05).There was no statistically significant difference in the adverse drug reactions during the treatment between the two groups( 字2=0.38，P>0.05).Conclusion：The plus minus Recipe Ⅱ for Ectopic Pregnancy united Mifepristone and Methotrexate(MTX) application in the treatment of tubal pregnancy，can achieve the purpose of quickly kill the pregnancy tissue and promote the absorption，has the important function of improving the treatment effect and reducing the pain of patients.
, http://www.100md.com
【Key words】 Tubal pregnancy； Mifepristone； Methotrexate； The decoction of ectopic pregnancy Ⅱ
First-author’s address：The People’s Hospital of Yongfeng County，Yongfeng 331500，China
doi：10.3969/j.issn.1674-4985.2015.32.033
异位妊娠在妇产科临床上是较常见疾病类型，其包括输卵管妊娠、腹腔妊娠、卵巢妊娠、间质部妊娠等[1-3]。其中输卵管妊娠发病率较高，据相关文献[4-5]报道，输卵管妊娠患者数量约占异位妊娠患者总数的95%左右。其多由输卵病变致管腔闭塞或狭窄，阻碍孕卵正常运行，使其在管腔内着床所致。患者临床症状主要表现为下腹单侧酸坠感或隐痛、停经、阴道不规则出血等，若输卵管妊娠破裂，可引发患者出现休克、晕厥、急性大出血等，从而危及患者生命安全[6]。为了探讨保守治疗输卵管妊娠有效途径，本文选取输卵管妊娠患者29例，在米非司酮联合甲氨喋呤治疗基础上加用宫外孕Ⅱ号方加减治疗，疗效颇为明显，现报告如下：, 百拇医药(彭春华)