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七叶皂苷纳合脊柱微创镇痛术治疗腰椎间盘突出症(1)
http://www.100md.com 2015年12月25日 中国医学创新 2015年第36期
     【摘要】 目的:观察七叶皂苷钠静滴合脊柱微创镇痛术治疗腰椎间盘突出症(LDH)的疗效。方法:选择2014年1月-2015年1月本院收治的60例腰椎间盘突出症患者作为研究对象,采用随机数字表法将其分为两组,每组30例,治疗组采用七叶皂苷钠合脊柱微创镇痛术疗法,对照组只采用脊柱微创镇痛术,观察比较两组疗效及不良反应等情况。结果:治疗组治疗后1周下腰痛评分低于对照组、治疗前及治疗后3个月,疗效优于对照组及治疗后3个月,比较差异均有统计学意义(P<0.05);治疗3个月后,两组疗效及下腰痛评分比较差异均无统计学意义(P>0.05)。两组均未出现明显不良反应。结论:七叶皂苷钠能明显提高脊柱微创镇痛术对腰椎间盘突出症的近期疗效。

    【关键词】 七叶皂苷钠; 脊柱微创镇痛术; 腰椎间盘突出症

    Sodium Aescinate Combined with Minimally Invasive Spine Analgesia in the Treatment of LDH/ZHANG Xu-qiao,WANG Xiao-hui,JIANG Sheng-ping,et al.//Medical Innovation of China,2015,12(36):019-022
, http://www.100md.com
    【Abstract】 Objective:To observe the effect of Sodium Aescinate combined with minimally invasive spine analgesia in the treatment of lumbar intervertebral disc hemiation(LDH).Method:60 patients with LDH in our hospital from January 2014 to January 2015 were selected and randomly divided into two groups,with each group 30 patients.The treatment group was treated with Sodium Aescinate combined with minimally invasive spine analgesia.The control group was treated with minimally invasive spine analgesia.The treatment effect and adverse reaction of the two groups were compared.Result:One week after the treatment,the score of low back pain of the treatment group was lower than that of the control group,that before treatment and that 3 months after the treatment,the curative effect of the treatment group was better than that of the control group and that 3 months after the treatment,the differences were all statistically significant(P<0.05).3 months after the treatment,the differences in the curative effect and scores of low back pain between the two groups were not statistically significant(P>0.05).The two groups had no significant adverse reactions.Conclusion:Sodium Aescinate in LDH patients with minimally invasive spine analgesia can improve the short-term effects.
, 百拇医药
    【Key words】 Sodium Aescinate; Minimally invasive spine analgesia; LDH

    First-author’s address:Traditional Chinese Medicine of Xiangtan City,Xiangtan 411100,China

    doi:10.3969/j.issn.1674-4985.2015.36.006

    腰椎间盘突出症是临床常见病、多发病,临床上有不少病例对常规保守治疗无效,但没有明显的开放手术指征,本科对该类患者采取了脊柱微创镇痛术结合七叶皂苷钠针静滴进行治疗,获得了满意的疗效,现报道如下。

    1 资料与方法

    1.1 一般资料 选择2014年1月-2015年1月本院脊柱外科收治的60例患者作为研究对象,采用随机数字表法将其分为两组,每组30例。治疗组男19例,女11例;年龄19~60岁,平均(36.8±6.8)岁;病程8 d~3年,平均(2.1±0.5)年;对照组男18例,女12例;年龄17~61岁,平均(37.2±6.6)岁;病程10 d~3年,平均(2.0±0.5)年。60例患者治疗前均经CT或/和MRI确诊为腰椎间盘突出症,且病变节段均为L4~5或L5~S1,其中治疗组L4~5突出者17例,L5~S1突出者13例,对照组L4~5突出者18例,L5~S1突出者12例,所有患者的突出椎间盘大小在水平面和矢状面上观察均未超过椎管前后径的1/2[1]。两组患者的一般资料比较差异均无统计学意义(P>0.05),具有可比性。, 百拇医药(张旭桥 王晓晖 姜升平 蒲云青 黄光明 仇湘中)
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