血管紧张素转化酶2—血管紧张素(1—7)—Mas轴在心血管和神经系统的作用(3)
参考文献
[1] Donoghue M，Hsieh F，Baronas E，et al.A novel angiotensin-converting enzyme-related carboxypeptidase(ACE2) converts angiotensinⅠto angiotensin 1-9[J].Circ Res，2000，87(5)：E1-E9.
[2] Santos R A，Simoes e Silva A C，Maric C，et al.Angiotensin-(1-7) is an endogenous ligand for the G protein-coupled receptor Mas[J].Proc Natl Acad Sci USA，2003，100(14)：8258-8263.
[3] Fraga-Silva1 R A，Costa-Fraga F P，Mur?a T M，et al.Angiotensin-converting enzyme 2 activation improves endothelia function[J].Hypertension，2013，61(6)：1233-1238.
, http://www.100md.com
[4] Rentzsch B，Todiras M，Iliescu R，et al.Transgenic angiotensin-converting enzyme 2 overexpression in vessels of SHRSP rats reduces blood pressure and improves endothelial function[J].Hypertension，2008，52(5)：967-973.
[5] Ferreira A J，Santos R A，Raizada M K.Angiotensin-(1-7)/angiotensin-converting enzyme2/mas receptor axis and related mechanisms[J].Int J Hypertens，2012，26(7)：690 785.
[6] Gomes E R，Santos R A，Guatimosim S.Angiotensin-(1-7)-mediated signaling in cardiomyocytes[J].Int J Hypertens，2012，36(6)：493 129.
, http://www.100md.com
[7] Sampaio W O，Henrique-de-Castro C，Santos R A，et al.Angiotensin-(1-7) counter regulates angiotensinⅠsignaling in human endothelial cells[J].Hypertension，2007，50(6)：1093-1098.
[8] Sampaio W O，Souza-dos-Santos R A，Faria-Silva R， et al.Angiotensin-(1-7) through receptor Mas mediates endothelial nitric oxide synthase activation via Akt-dependent pathways[J].Hypertension，2007，49(1)：185-192.
[9] Crackower M A，Sarao R，Oudit G Y，et al.Angiotensin-converting enzyme 2 is an essential regulator of heart function[J]. Nature，2002，417(6891)：822-828.
, http://www.100md.com
[10] Huentelman M J，Grobe J L，Vazquez J，et al.Protection from angiotensin Ⅱ-induced cardiac hypertrophy and fibrosis by systemic lentiviral delivery of ACE2 in rats[J].Exp Physiol，2005，90(5)：783-790.
[11] Díez-Freire C，Vázquez J，Correa de Adjounian M F，et al.ACE2 gene transfer attenuates hypertension-linked pathophysiological changes in the SHR[J].Physiol Genomics，2006，27(1)：12-19.
[12] Touyz R M.Reactive oxygen species and angiotensin Ⅱ signaling in vascular cells-implications in cardiovascular disease[J]. Braz J Med Biol Res，2004，37(8)：1263-1273.
, http://www.100md.com
[13] Unger T.The role of the renin-angiotensin system in the development of cardiovascular disease[J].Am J Cardiol，2002，89(2)：3A-9A.
[14] Wang J，Li N，Gao F，et al.Balance between angiotensin converting enzyme and angiotensin converting enzyme 2 in patients with chronic heart failure[J].J Renin Angiotensin Aldosterone Syst，2015，16(3)：553-558., 百拇医药(王晶晶 梁广彬 邓凡 卢悦 张良清)
[1] Donoghue M，Hsieh F，Baronas E，et al.A novel angiotensin-converting enzyme-related carboxypeptidase(ACE2) converts angiotensinⅠto angiotensin 1-9[J].Circ Res，2000，87(5)：E1-E9.
[2] Santos R A，Simoes e Silva A C，Maric C，et al.Angiotensin-(1-7) is an endogenous ligand for the G protein-coupled receptor Mas[J].Proc Natl Acad Sci USA，2003，100(14)：8258-8263.
[3] Fraga-Silva1 R A，Costa-Fraga F P，Mur?a T M，et al.Angiotensin-converting enzyme 2 activation improves endothelia function[J].Hypertension，2013，61(6)：1233-1238.
, http://www.100md.com
[4] Rentzsch B，Todiras M，Iliescu R，et al.Transgenic angiotensin-converting enzyme 2 overexpression in vessels of SHRSP rats reduces blood pressure and improves endothelial function[J].Hypertension，2008，52(5)：967-973.
[5] Ferreira A J，Santos R A，Raizada M K.Angiotensin-(1-7)/angiotensin-converting enzyme2/mas receptor axis and related mechanisms[J].Int J Hypertens，2012，26(7)：690 785.
[6] Gomes E R，Santos R A，Guatimosim S.Angiotensin-(1-7)-mediated signaling in cardiomyocytes[J].Int J Hypertens，2012，36(6)：493 129.
, http://www.100md.com
[7] Sampaio W O，Henrique-de-Castro C，Santos R A，et al.Angiotensin-(1-7) counter regulates angiotensinⅠsignaling in human endothelial cells[J].Hypertension，2007，50(6)：1093-1098.
[8] Sampaio W O，Souza-dos-Santos R A，Faria-Silva R， et al.Angiotensin-(1-7) through receptor Mas mediates endothelial nitric oxide synthase activation via Akt-dependent pathways[J].Hypertension，2007，49(1)：185-192.
[9] Crackower M A，Sarao R，Oudit G Y，et al.Angiotensin-converting enzyme 2 is an essential regulator of heart function[J]. Nature，2002，417(6891)：822-828.
, http://www.100md.com
[10] Huentelman M J，Grobe J L，Vazquez J，et al.Protection from angiotensin Ⅱ-induced cardiac hypertrophy and fibrosis by systemic lentiviral delivery of ACE2 in rats[J].Exp Physiol，2005，90(5)：783-790.
[11] Díez-Freire C，Vázquez J，Correa de Adjounian M F，et al.ACE2 gene transfer attenuates hypertension-linked pathophysiological changes in the SHR[J].Physiol Genomics，2006，27(1)：12-19.
[12] Touyz R M.Reactive oxygen species and angiotensin Ⅱ signaling in vascular cells-implications in cardiovascular disease[J]. Braz J Med Biol Res，2004，37(8)：1263-1273.
, http://www.100md.com
[13] Unger T.The role of the renin-angiotensin system in the development of cardiovascular disease[J].Am J Cardiol，2002，89(2)：3A-9A.
[14] Wang J，Li N，Gao F，et al.Balance between angiotensin converting enzyme and angiotensin converting enzyme 2 in patients with chronic heart failure[J].J Renin Angiotensin Aldosterone Syst，2015，16(3)：553-558., 百拇医药(王晶晶 梁广彬 邓凡 卢悦 张良清)