脑白质疏松症及相关认知障碍的研究进展(4)
[15] Fernando Malee S， Simpson Julie E， Matthews Fiona， et al. White matter lesions in an unselected cohort of the elderly： molecular pathology suggests origin from chronic hypoperfusion injury[J]. Stroke， 2006，37(6)：1391-1398.
[16] Munoz David G. Leukoaraiosis and ischemia： beyond the myth[J]. Stroke， 2006，37(6)：1348-1349.
[17] Te M， Zhao E， Zheng X Y， et al. Leukoaraiosis with mild cognitive impairment[J]. Neuroll Res， 2015， Early Online： 1743132815Y0000000028.
, http://www.100md.com
[18] Grueter Basil E， Schulz Ursula G. Age-related cerebral white matter disease (leukoaraiosis)： a review[J]. Postgrad Med J， 2012，88(1036)：79-87.
[19] Stevenson S F， Doubal F N， Shuler K， et al. A systematic review of dynamic cerebral and peripheral endothelial function in lacunar stroke versus controls[J]. Stroke， 2010，41(6)：434-442.
[20] Hou X， Liang X， Chen J F， et al. Ecto-5’-nucleotidase (CD73) is involved in chronic cerebral hypoperfusion-induced white matter lesions and cognitive impairment by regulating glial cell activetion and pro-inflammatory cytokings[J].Neuroscience， 2015， 297(12)：118-126.
, http://www.100md.com
[21] Anna P， Alida G， van der Flier W， et al. Cerebral white matter changes are associated with abnormalities on neurological examination in non-disabled elderly： the LADIS study[J]. J Neurol， 2013，260(4)：1014-1021.
[22] Otsuka Y， Yamauchi H， Sawamoto N， et al. Diffuse tract damage in the hemispheric deep white matter may correlate with global cognitive impairment and callosal atrophy in patients with extensive leukoaraiosis[J]. AJNR Am J Neuroradiol， 2012， 33(4)：726-732.
, http://www.100md.com
[23] Jokinen H， Schmidt R， Ropele S， et al. Diffusion changes predict cognitive and functional outcome： The LADIS study[J]. Ann Neurol， 2013，73(5)：576-583.
[24] Macfarlane M D， Looi J C L， Walterfang M， et al. Executive dysfunction correlates with caudate nucleus atrophy in patients with white matter changes on MRI： A subset of LADIS[J]. Psychiatry Res， 2013，214(1)：16-23.
[25] Anil M T， Andrew T R， Elena S， et al. Relationship between white matter hyperintensities，cortical thickness， and cognition[J]. Stroke， 2015， 46(2)：425-432.
, http://www.100md.com
[26] MohdTaib N H， Wan Abdullah A K， Shuaib I L， et al. Diffusion tensor magnetic resonance imaging as molecular diagnostic tool for leukoaraiosis[J].Asian Pacific Journal of Tropical Disease， 2014， 4 (3)：228.
[27] Dini Leandro I， Vedolin Leonardo M， Bertholdo Debora， et al. Reproducibility of quantitative fiber tracking measurements in diffusion tensor imaging of frontal lobe tracts： A protocol based on the fiber dissection technique[J]. Surg Neurol Int， 2013，58(4)：51.
, 百拇医药
[28] Zemmoura Ilyess， Serres Barthélémy， Andersson Frédéric， et al. FIBRASCAN： A novel method for 3D white matter tract reconstruction in MR space from cadaveric dissection[J]. Neuroimage， 2014，58(103C)：106-118.
[29] Sun X， Liang Y， Wang J， et al. Early frontal structural and functional changes in mild white matter lesions relevant to cognitive decline[J]. J Alzheimers Dis，2014，40(1)，123-134.
[30] Wang S K， Yuan J L， Guo X J， et al. Neurochemical correlates of cognitive dysfunction in patients with leukoaraiosis： a proton magnetic resonance spectroscopy study[J]. Neurol Res， 2012，34(10)：989-997.
(收稿日期：2015-09-26) (本文编辑：蔡元元), 百拇医药(李倩 胡风云 赵路清)
[16] Munoz David G. Leukoaraiosis and ischemia： beyond the myth[J]. Stroke， 2006，37(6)：1348-1349.
[17] Te M， Zhao E， Zheng X Y， et al. Leukoaraiosis with mild cognitive impairment[J]. Neuroll Res， 2015， Early Online： 1743132815Y0000000028.
, http://www.100md.com
[18] Grueter Basil E， Schulz Ursula G. Age-related cerebral white matter disease (leukoaraiosis)： a review[J]. Postgrad Med J， 2012，88(1036)：79-87.
[19] Stevenson S F， Doubal F N， Shuler K， et al. A systematic review of dynamic cerebral and peripheral endothelial function in lacunar stroke versus controls[J]. Stroke， 2010，41(6)：434-442.
[20] Hou X， Liang X， Chen J F， et al. Ecto-5’-nucleotidase (CD73) is involved in chronic cerebral hypoperfusion-induced white matter lesions and cognitive impairment by regulating glial cell activetion and pro-inflammatory cytokings[J].Neuroscience， 2015， 297(12)：118-126.
, http://www.100md.com
[21] Anna P， Alida G， van der Flier W， et al. Cerebral white matter changes are associated with abnormalities on neurological examination in non-disabled elderly： the LADIS study[J]. J Neurol， 2013，260(4)：1014-1021.
[22] Otsuka Y， Yamauchi H， Sawamoto N， et al. Diffuse tract damage in the hemispheric deep white matter may correlate with global cognitive impairment and callosal atrophy in patients with extensive leukoaraiosis[J]. AJNR Am J Neuroradiol， 2012， 33(4)：726-732.
, http://www.100md.com
[23] Jokinen H， Schmidt R， Ropele S， et al. Diffusion changes predict cognitive and functional outcome： The LADIS study[J]. Ann Neurol， 2013，73(5)：576-583.
[24] Macfarlane M D， Looi J C L， Walterfang M， et al. Executive dysfunction correlates with caudate nucleus atrophy in patients with white matter changes on MRI： A subset of LADIS[J]. Psychiatry Res， 2013，214(1)：16-23.
[25] Anil M T， Andrew T R， Elena S， et al. Relationship between white matter hyperintensities，cortical thickness， and cognition[J]. Stroke， 2015， 46(2)：425-432.
, http://www.100md.com
[26] MohdTaib N H， Wan Abdullah A K， Shuaib I L， et al. Diffusion tensor magnetic resonance imaging as molecular diagnostic tool for leukoaraiosis[J].Asian Pacific Journal of Tropical Disease， 2014， 4 (3)：228.
[27] Dini Leandro I， Vedolin Leonardo M， Bertholdo Debora， et al. Reproducibility of quantitative fiber tracking measurements in diffusion tensor imaging of frontal lobe tracts： A protocol based on the fiber dissection technique[J]. Surg Neurol Int， 2013，58(4)：51.
, 百拇医药
[28] Zemmoura Ilyess， Serres Barthélémy， Andersson Frédéric， et al. FIBRASCAN： A novel method for 3D white matter tract reconstruction in MR space from cadaveric dissection[J]. Neuroimage， 2014，58(103C)：106-118.
[29] Sun X， Liang Y， Wang J， et al. Early frontal structural and functional changes in mild white matter lesions relevant to cognitive decline[J]. J Alzheimers Dis，2014，40(1)，123-134.
[30] Wang S K， Yuan J L， Guo X J， et al. Neurochemical correlates of cognitive dysfunction in patients with leukoaraiosis： a proton magnetic resonance spectroscopy study[J]. Neurol Res， 2012，34(10)：989-997.
(收稿日期：2015-09-26) (本文编辑：蔡元元), 百拇医药(李倩 胡风云 赵路清)