【摘要】 目的：探索初治继发性肺结核患者中医(TCM)证候分布规律及证型与干扰素-γ的相关性。方法：选取2009年10月-2010年12月分布在全国14家分中心的1500例初治继发性肺结核患者进行基本信息、中医证型信息等采集，建立中医证候数据库、检测指标数据库，对患者信息进行统计分析。结果：占前3位的证型分别为肺阴虚证(40.3%)、阴虚火旺证(20.4%)、气阴两虚证(19.5%)；证型分布占比最小的为瘀阻肺络证(0.1%)。肝火犯肺证、肺气虚证、痰热壅肺证、肺脾气虚证与干扰素-γ密切相关(P<0.05)。结论：干扰素-γ在细胞免疫调节中具重要作用，而初治继发性肺结核患者各证型与干扰素相关性不同，为中医辨证施治提供客观依据，具重要参考价值。

    【关键词】 初治继发性肺结核； 干扰素-γ

    【Abstract】 Objective：To explore the distribution of TCM syndromes and the correlation between TCM syndromes and Interferon-γ in the initial treatment of patients with secondary pulmonary tuberculosis.Method：One thousand and five hundred cases of patients with initial treatment secondary pulmonary tuberculosis from October 2009 to December 2010 were collected from 14 branch centers in the whole country.The essential information and syndrome types of these patients were collected and analyzed through the foundation of TCM syndromes database and the detection of indicator database.Result：The syndrome types of the top three were lung yin deficiency syndrome(40.3%) ......