某社区成年女性代谢综合征与相应血常规指标相关性研究(1)
【摘要】 目的：探讨成年女性代谢综合征(metabolic syndrome，MS)的发生与相应血常规指标的关联性。方法：选取来自广州市某社区卫生服务中心的成年女性体检者共2280例作为研究对象，按照是否患有MS分为MS组348例，非MS组1932例。比较两组的白细胞计数(WBC)、红细胞计数(RBC)、血红蛋白(HGB)、平均红细胞体积(MCV)、平均红细胞血红蛋白含量(MCH)、平均红细胞血红蛋白浓度(MCHC)、红细胞体积分布宽度(RDW)、血小板计数(PLT)、平均血小板体积(MPV)、血小板体积分布宽度(PDW)、淋巴细胞绝对值、嗜中性粒细胞绝对值，分析这些血常规指标与MS的相关性。根据所含异常代谢组分的不同将人群分为MS0、MS1、MS2、MS3、MS4组，分析各组间血常规指标的差异。结果：MS组的WBC、RBC、HGB、RDW、淋巴细胞绝对值、嗜中性粒细胞绝对值均显著高于非MS组(P<0.05)，WBC、HGB、淋巴细胞绝对值、嗜中性粒细胞绝对值随着代谢异常组分的增加而增加。结论：广州市某社区成年女性体检中WBC、RBC、HGB、RDW、淋巴细胞绝对值、嗜中性粒细胞绝对值这几项血常规指标与MS的发生具有相关性，这几项血细胞参数的改变，可能与MS的发病风险有关。
【关键词】 代谢综合征； 血常规指标
Study of the Relationships Between Female metabolic Syndrome and Its Related Blood Indexes in Guangzhou/WANG Ting，WANG Hao.//Medical Innovation of China，2016，13(35)：061-064
【Abstract】 Objective：To evaluate the relationship between female metabolic syndrome (MS) and its related blood indexes in a community of Guangzhou City adults’ population.Method：2280 subjects，adult female from Community Health Center，were divided into two groups：MS group(n=348)and no MS group(n=1932).White blood cell count(WBC)，red blood cell count(RBC)，hemoglobin(HGB)，mean corpuscular volume(MCV)，mean corpuscular hemoglobin(MCH)，mean corpuscular hemoglobin concentration(MCHC)，red blood cell volume distribution width(RDW)，platelet count(PLT)，mean platelet volume(MPV)，platelet volume distribution width(PDW)，absolute lymphocytes，neutrophils absolute value of two groups were compared.The correlation between blood indicators and MS were analyzed.Result：WBC，RBC，HGB，RDW，absolute lymphocytes and neutrophils absolute value were significantly higher than no MS group(P<0.05).The absolute value of WBC，HGB，lymphocyte and neutrophil absolute value increased with the increase of the metabolic components.Conclusion：Blood indicators is correlated with metabolic syndrome and they are potential predictors for metabolic syndrome.
【Key words】 Metabolic syndrome； Blood indexes
First-author’s address：School of Public Health，Guangdong Pharmaceutical University，Guangzhou 510006，China
doi：10.3969/j.issn.1674-4985.2016.35.015
在我國11个省市进行抽样调查结果显示，27 739例年龄在35～64岁的调查对象中，代谢综合征(metabolic syndrome，MS)的患病率达到了13.3%(男性12.7%，女性14.2%)[1]。MS是中心性肥胖、血脂异常、高血压及高血糖多种代谢疾病合并出现的临床症候群，与肥胖和胰岛素抵抗关系密切。研究发现MS可以增加糖尿病、心血管疾病、慢性肾脏疾病、非酒精性脂肪性肝病等多种疾病的致残率和致死率[2]。MS的发病机制并未研究清楚，但大量的研究证明MS与亚临床的慢性炎症相关[3]。红细胞计数、血红蛋白、血小板等血常规指标影响血液凝集状态，代表机体炎性反应，而研究发现慢性炎性反应和血液凝集状态与MS密切相关[4-6]。为此笔者选择了成年女性体检者，比较MS患者与非MS患者各项血液检查指标的差异，探讨血常规指标与MS的相关性，为MS的早发现、早预防提供理论依据，现报道如下。, http://www.100md.com(王婷 王浩)
【关键词】 代谢综合征； 血常规指标
Study of the Relationships Between Female metabolic Syndrome and Its Related Blood Indexes in Guangzhou/WANG Ting，WANG Hao.//Medical Innovation of China，2016，13(35)：061-064
【Abstract】 Objective：To evaluate the relationship between female metabolic syndrome (MS) and its related blood indexes in a community of Guangzhou City adults’ population.Method：2280 subjects，adult female from Community Health Center，were divided into two groups：MS group(n=348)and no MS group(n=1932).White blood cell count(WBC)，red blood cell count(RBC)，hemoglobin(HGB)，mean corpuscular volume(MCV)，mean corpuscular hemoglobin(MCH)，mean corpuscular hemoglobin concentration(MCHC)，red blood cell volume distribution width(RDW)，platelet count(PLT)，mean platelet volume(MPV)，platelet volume distribution width(PDW)，absolute lymphocytes，neutrophils absolute value of two groups were compared.The correlation between blood indicators and MS were analyzed.Result：WBC，RBC，HGB，RDW，absolute lymphocytes and neutrophils absolute value were significantly higher than no MS group(P<0.05).The absolute value of WBC，HGB，lymphocyte and neutrophil absolute value increased with the increase of the metabolic components.Conclusion：Blood indicators is correlated with metabolic syndrome and they are potential predictors for metabolic syndrome.
【Key words】 Metabolic syndrome； Blood indexes
First-author’s address：School of Public Health，Guangdong Pharmaceutical University，Guangzhou 510006，China
doi：10.3969/j.issn.1674-4985.2016.35.015
在我國11个省市进行抽样调查结果显示，27 739例年龄在35～64岁的调查对象中，代谢综合征(metabolic syndrome，MS)的患病率达到了13.3%(男性12.7%，女性14.2%)[1]。MS是中心性肥胖、血脂异常、高血压及高血糖多种代谢疾病合并出现的临床症候群，与肥胖和胰岛素抵抗关系密切。研究发现MS可以增加糖尿病、心血管疾病、慢性肾脏疾病、非酒精性脂肪性肝病等多种疾病的致残率和致死率[2]。MS的发病机制并未研究清楚，但大量的研究证明MS与亚临床的慢性炎症相关[3]。红细胞计数、血红蛋白、血小板等血常规指标影响血液凝集状态，代表机体炎性反应，而研究发现慢性炎性反应和血液凝集状态与MS密切相关[4-6]。为此笔者选择了成年女性体检者，比较MS患者与非MS患者各项血液检查指标的差异，探讨血常规指标与MS的相关性，为MS的早发现、早预防提供理论依据，现报道如下。, http://www.100md.com(王婷 王浩)