急性髓细胞白血病表观遗传学的靶向性和个体化治疗策略(4)
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[18] Harris W J，Huang X，Lynch J T，et al.The histone demethylase KDM1A sustains the oncogenic potential of MLL-AF9 leukemia stem cells[J].Cancer Cell，2012，21(4)：473-487.
[19] Ding L，Ley T J，Larson D E，et al.Clonal evolution in relapsed acute myeloid leukemia revealed by whole-genome sequencing[J].Nature，2012，481(7382)：506-510.
[20] Klco J M，Spencer D H，Miller C A，et al.Functional heterogeneity of genetically defined subclones in acute myeloid leukemia[J].Cancer Cell，2014，25(3)：379-392.
[21] Marcucci G，Yan P，Maharry K，et al.Epigenetics meets genetics in acute myeloid leukemia：clinical impact of a novel seven-gene score[J].J Clin Oncol，2014，32(6)：548-556.
(收稿日期：2017-01-18) (本文編辑：程旭然), 百拇医药(庞家秉)
[16] Prebet T，Sun Z，Figueroa M E，et al.Prolonged administration of azacitidine with or without entinostat for myelodysplastic syndrome and acute myeloid leukemia with myelodysplasia-related changes：results of the US leukemia Imtergroup trial E1905[J].J Clin Oncol，2014，32(12)：1242-1248.
[17] Zuber J，Shi J，Wang E，et al.RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukemia[J].Nature，2011，478(7370)：524-528.
[18] Harris W J，Huang X，Lynch J T，et al.The histone demethylase KDM1A sustains the oncogenic potential of MLL-AF9 leukemia stem cells[J].Cancer Cell，2012，21(4)：473-487.
[19] Ding L，Ley T J，Larson D E，et al.Clonal evolution in relapsed acute myeloid leukemia revealed by whole-genome sequencing[J].Nature，2012，481(7382)：506-510.
[20] Klco J M，Spencer D H，Miller C A，et al.Functional heterogeneity of genetically defined subclones in acute myeloid leukemia[J].Cancer Cell，2014，25(3)：379-392.
[21] Marcucci G，Yan P，Maharry K，et al.Epigenetics meets genetics in acute myeloid leukemia：clinical impact of a novel seven-gene score[J].J Clin Oncol，2014，32(6)：548-556.
(收稿日期：2017-01-18) (本文編辑：程旭然), 百拇医药(庞家秉)