在基因检测指导下非小细胞肺癌患者接受表皮生长因子受体酪氨酸激酶抑制剂治疗临床疗效比较(5)
[16] Won Y W，Han J Y，Lee G K，et al.Comparison of clinical outcome of patients with non-small-cell lung cancer harbouring epidermal growth factor receptor exon 19 or exon 21 mutations[J].
J Clin Pathol，2011，64(11)：947-952.
[17] Jackman D M，Yeap B Y，Sequist L V，et al.Exon 19 deletion mutations of epidermal growth factor receptor are associated with prolonged survival in non-small cell lung cancer patients treated with gefitinib or erlotinib[J].Clin Cancer Res，2006，12(13)：3908-3914.
[18] Li J，Qu L，Wei X，et al.Clinical observation of EGFR-TKI as a first-line therapy on advanced non-small cell lung cancer[J].Chinese Journal of Lung Cancer，2012，15(5)：299-304.
[19] Sun J M，Won Y W，Kim S T，et al.The different efficacy of gefitinib or erlotinib according to epidermal growth factor receptor exon 19 and exon 21 mutations in Korean non-small cell lung cancer patients[J].J Cancer Res，2011，137(4)：687-694.
[20] Tan C S，Gilligan D，Pacey S.Treatment approaches for EGFR-inhibitor-resistant patients with non-small-cell lung cancer[J].Lancet Oncol，2015，16(9)：e447-e459.
[21] Ciardiello F，Tortora G.EGFR antagonists in cancer treatment[J].N Engl J Med，2008，358(11)：1160-1174.
(收稿日期：2017-09-25) (本文編辑：董悦), http://www.100md.com(王黎铭 尹俊 刘书琴 偰燕燕 范钰)
J Clin Pathol，2011，64(11)：947-952.
[17] Jackman D M，Yeap B Y，Sequist L V，et al.Exon 19 deletion mutations of epidermal growth factor receptor are associated with prolonged survival in non-small cell lung cancer patients treated with gefitinib or erlotinib[J].Clin Cancer Res，2006，12(13)：3908-3914.
[18] Li J，Qu L，Wei X，et al.Clinical observation of EGFR-TKI as a first-line therapy on advanced non-small cell lung cancer[J].Chinese Journal of Lung Cancer，2012，15(5)：299-304.
[19] Sun J M，Won Y W，Kim S T，et al.The different efficacy of gefitinib or erlotinib according to epidermal growth factor receptor exon 19 and exon 21 mutations in Korean non-small cell lung cancer patients[J].J Cancer Res，2011，137(4)：687-694.
[20] Tan C S，Gilligan D，Pacey S.Treatment approaches for EGFR-inhibitor-resistant patients with non-small-cell lung cancer[J].Lancet Oncol，2015，16(9)：e447-e459.
[21] Ciardiello F，Tortora G.EGFR antagonists in cancer treatment[J].N Engl J Med，2008，358(11)：1160-1174.
(收稿日期：2017-09-25) (本文編辑：董悦), http://www.100md.com(王黎铭 尹俊 刘书琴 偰燕燕 范钰)