四维彩超在胎儿唇裂畸形产前诊断中的价值及效果(1)
【摘要】 目的：探讨四维彩超在胎儿唇裂畸形产前诊断中的价值及效果，为临床诊断提供参考。方法：选取2015年5月-2017年5月本院经二维超声检查后疑似唇裂畸形胎儿20例，通过四维彩超进行二次诊断，对比诊断结果。结果：20例唇裂胎儿中，单纯唇裂5例，二维超声检查确诊2例(40.00%)，四维彩超检查确诊5例(100%)，比较差异有统计学意义(P<0.05)；唇裂合并完全性腭裂14例，二维超声检查确诊7例(50.00%)，四维彩超检查确诊12例(85.71%)，比较差异有统计学意义(P<0.05)；唇裂合并不完全性腭裂1例，二维超声与四维彩超均未诊出。15例单侧唇腭裂，二维超声误诊6例(40.00%)，四维彩超误诊1例(6.67%)，比较差异有统计学意义(P<0.05)；5例非單侧唇腭裂，二维超声误诊4例(80.00%)，四维彩超误诊0例，比较差异有统计学意义(P<0.05)。结论：四维彩超应用于产前诊断胎儿唇裂畸形具有良好的效果，二维超声对单纯唇裂和唇裂合并完全性腭裂的诊断率基本相似，而四维彩超对唇裂合并完全性腭裂的诊断准确率明显较高，且能准确判断唇裂为单侧还是非单侧，误诊率较低，值得在临床推广应用。
【关键词】 四维彩超； 唇裂畸形； 产前诊断； 诊断价值
【Abstract】 Objective：To explore the value and effect of four-dimensional color Doppler ultrasound in prenatal diagnosis of fetal cleft lip deformity，to provide reference for clinical diagnosis.Method：20 cases of suspected cleft lip fetus after two-dimensional ultrasound examination from May 2015 to May 2017 in our hospital were selected，through four-dimensional color Doppler ultrasound for two times diagnosis，the diagnosis results were compared.Result：In 20 cases of cleft lip，5 cases of simple cleft lip，2 cases(40.00%) were diagnosed by two-dimensional ultrasound，5 cases(100%) were diagnosed by four-dimensional color Doppler ultrasound，the difference was statistically significant(P<0.05).14 cases of cleft lip with complete cleft palate，7(50.00%) cases were diagnosed by two-dimensional ultrasound，12 cases(85.71%) were diagnosed by four-dimensional color Doppler ultrasound，the difference was statistically significant(P<0.05).1 case of cleft lip with incomplete cleft palate were not diagnosed by two-dimensional ultrasound and four-dimensional color Doppler ultrasound.15 cases were unilateral cleft lip and palate，6 cases(40.00%) were misdiagnosed by two-dimensional ultrasound，1 case(6.67%) were misdiagnosed by four-dimensional color Doppler ultrasound，the difference was statistically significant(P<0.05).5 cases of non unilateral cleft lip and palate，4 cases(80.00%) were misdiagnosed by two-dimensional ultrasound，0 case were misdiagnosed by four-dimensional color Doppler ultrasound，the difference was statistically significant(P<0.05).Conclusion：Four-dimensional color Doppler ultrasound has a good effect on prenatal diagnosis of fetal cleft lip deformity，compared with two-dimensional ultrasound，two-dimensional ultrasound has a similar diagnosis rate for cleft lip and cleft lip with complete cleft palate，while four-dimensional color Doppler ultrasound has higher accuracy in diagnosis of cleft lip with complete cleft palate，and can accurately determine the cleft lip is unilateral or non-unilateral，and the misdiagnosis rate is low，so it is worthy of clinical application., http://www.100md.com(涂淑萍 熊伟红)
【关键词】 四维彩超； 唇裂畸形； 产前诊断； 诊断价值
【Abstract】 Objective：To explore the value and effect of four-dimensional color Doppler ultrasound in prenatal diagnosis of fetal cleft lip deformity，to provide reference for clinical diagnosis.Method：20 cases of suspected cleft lip fetus after two-dimensional ultrasound examination from May 2015 to May 2017 in our hospital were selected，through four-dimensional color Doppler ultrasound for two times diagnosis，the diagnosis results were compared.Result：In 20 cases of cleft lip，5 cases of simple cleft lip，2 cases(40.00%) were diagnosed by two-dimensional ultrasound，5 cases(100%) were diagnosed by four-dimensional color Doppler ultrasound，the difference was statistically significant(P<0.05).14 cases of cleft lip with complete cleft palate，7(50.00%) cases were diagnosed by two-dimensional ultrasound，12 cases(85.71%) were diagnosed by four-dimensional color Doppler ultrasound，the difference was statistically significant(P<0.05).1 case of cleft lip with incomplete cleft palate were not diagnosed by two-dimensional ultrasound and four-dimensional color Doppler ultrasound.15 cases were unilateral cleft lip and palate，6 cases(40.00%) were misdiagnosed by two-dimensional ultrasound，1 case(6.67%) were misdiagnosed by four-dimensional color Doppler ultrasound，the difference was statistically significant(P<0.05).5 cases of non unilateral cleft lip and palate，4 cases(80.00%) were misdiagnosed by two-dimensional ultrasound，0 case were misdiagnosed by four-dimensional color Doppler ultrasound，the difference was statistically significant(P<0.05).Conclusion：Four-dimensional color Doppler ultrasound has a good effect on prenatal diagnosis of fetal cleft lip deformity，compared with two-dimensional ultrasound，two-dimensional ultrasound has a similar diagnosis rate for cleft lip and cleft lip with complete cleft palate，while four-dimensional color Doppler ultrasound has higher accuracy in diagnosis of cleft lip with complete cleft palate，and can accurately determine the cleft lip is unilateral or non-unilateral，and the misdiagnosis rate is low，so it is worthy of clinical application., http://www.100md.com(涂淑萍 熊伟红)