富马酸亚铁单独治疗与联合健脾生血颗粒治疗小儿缺铁性贫血的疗效(1)
【摘要】 目的：比较小儿缺铁性贫血采取富马酸亚铁单独治疗与联合健脾生血颗粒治疗的疗效。方法：选择2015年1月-2017年6月本院收治的小儿缺铁性贫血患儿66例进行研究，按照治疗方案不同分为两组，对照组32例单用富马酸亚铁治疗，治疗组34例采取富马酸亚铁与健脾生血颗粒联合治疗。对两组患儿临床疗效进行评价，记录不良反应，并检测治疗前后MCV、铁蛋白、血清铁、Hb、MCH。结果：治疗组患者不良反应发生率显著低于对照组(P<0.05)；两组患者治疗前MCV、铁蛋白、血清铁、Hb、MCH比较差异均无统计学意义(P>0.05)，治疗后治疗组均显著优于对照组(P<0.05)。结论：小儿缺铁性贫血患儿采取富马酸亚铁联合健脾生血颗粒治疗，相比单用富马酸亚铁治疗疗效更好，安全性更高，而且能更好地改善血液指标，值得推荐。
【关键词】 小儿； 缺铁性贫血； 富马酸亚铁； 健脾生血颗粒
Treatment of Iron Deficiency Anemia in Children with Ferrous Fumarate Alone and Combination with Jianpi Shengqi Granule/XIAO Zhen，WU Weizhao.//Medical Innovation of China，2018，15(01)：140-142
, http://www.100md.com
【Abstract】 Objective：To compare the efficacy of ferrous fumarate alone or combination with Jianpi Shengqi Granule in children with iron deficiency anemia.Method：A total of 66 children with iron deficiency anemia were selected from January 2015 to June 2017. According to the treatment plan they were divided into two groups，the control group of 32 patients with ferrous fumarate alone，the treatment group of 34 cases were given ferrous fumarate combined with Jianpi Shengqi Granule.The clinical efficacy of the two groups was evaluated.Adverse reactions were recorded，the levels of MCV，ferritin，serum iron，Hb and MCH were measured before and after treatment.Result：The incidence of adverse reactions in the treatment group was significantly lower than that in the control group (P<0.05).Before treatment，the levels of MCV，ferritin，serum iron，Hb and MCH of two groups compared，there was no significant difference(P>0.05)；after treatment，those levels of treatment group were better than control group(P<0.05).Conclusion：The treatment of children with iron deficiency anemia in ferrous fumarate combined with and Jianpi Shengqi Granule is better than that of ferrous fumarate alone，the safety is higher，and the blood index improved better，it is worthy learning.
, 百拇医药
【Key words】 Children； Iron deficiency anemia； Ferrous Fumarate； Jianpi Shengqi Granule
First-author’s address：Xiaolan Hospital Affiliated to Southern Medical University，Zhongshan 528415，China
doi：10.3969/j.issn.1674-4985.2018.01.039
缺鐵性贫血属于小儿常见营养缺乏性疾病，据相关文献[1]报道指出，我国学龄前儿童发生缺铁性贫血达到23%左右。缺铁性贫血除了会对小儿血液系统造成影响，还可能对神经系统发育造成阻碍[2]。此外，小儿严重缺铁性贫血可诱发大脑不可逆永久性伤害，威胁他们的生长发育[3]。基于此，针对小儿缺铁性贫血要尽早发现、诊断及治疗，避免并发症发生[4]。铁剂是治疗本病主要药物，选用依从性良好、安全有效的药物治疗是关键[5]。为了进一步探讨小儿缺铁性贫血采取富马酸亚铁单独治疗与联合健脾生血颗粒治疗的疗效，本院将收治的66例患儿进行了如下研究，现报道如下。
1 资料与方法
1.1 一般资料 选择本院2015年1月-2017年6月收治的小儿缺铁性贫血患儿66例进行研究，纳入标准：确诊符合缺铁性贫血诊断标准[6]；近期无铁剂应用史；家长愿意配合研究，且签署知情同意书。排除标准：近1个月内应用铁剂；严重心肝肾等脏器病变；2周内有腹泻或慢性感染等。按照治疗方案不同分为两组，对照组32例单用富马酸亚铁治疗，治疗组34例采取富马酸亚铁与健脾生血颗粒联合治疗。, http://www.100md.com(肖贞 吴卫照)
【关键词】 小儿； 缺铁性贫血； 富马酸亚铁； 健脾生血颗粒
Treatment of Iron Deficiency Anemia in Children with Ferrous Fumarate Alone and Combination with Jianpi Shengqi Granule/XIAO Zhen，WU Weizhao.//Medical Innovation of China，2018，15(01)：140-142
, http://www.100md.com
【Abstract】 Objective：To compare the efficacy of ferrous fumarate alone or combination with Jianpi Shengqi Granule in children with iron deficiency anemia.Method：A total of 66 children with iron deficiency anemia were selected from January 2015 to June 2017. According to the treatment plan they were divided into two groups，the control group of 32 patients with ferrous fumarate alone，the treatment group of 34 cases were given ferrous fumarate combined with Jianpi Shengqi Granule.The clinical efficacy of the two groups was evaluated.Adverse reactions were recorded，the levels of MCV，ferritin，serum iron，Hb and MCH were measured before and after treatment.Result：The incidence of adverse reactions in the treatment group was significantly lower than that in the control group (P<0.05).Before treatment，the levels of MCV，ferritin，serum iron，Hb and MCH of two groups compared，there was no significant difference(P>0.05)；after treatment，those levels of treatment group were better than control group(P<0.05).Conclusion：The treatment of children with iron deficiency anemia in ferrous fumarate combined with and Jianpi Shengqi Granule is better than that of ferrous fumarate alone，the safety is higher，and the blood index improved better，it is worthy learning.
, 百拇医药
【Key words】 Children； Iron deficiency anemia； Ferrous Fumarate； Jianpi Shengqi Granule
First-author’s address：Xiaolan Hospital Affiliated to Southern Medical University，Zhongshan 528415，China
doi：10.3969/j.issn.1674-4985.2018.01.039
缺鐵性贫血属于小儿常见营养缺乏性疾病，据相关文献[1]报道指出，我国学龄前儿童发生缺铁性贫血达到23%左右。缺铁性贫血除了会对小儿血液系统造成影响，还可能对神经系统发育造成阻碍[2]。此外，小儿严重缺铁性贫血可诱发大脑不可逆永久性伤害，威胁他们的生长发育[3]。基于此，针对小儿缺铁性贫血要尽早发现、诊断及治疗，避免并发症发生[4]。铁剂是治疗本病主要药物，选用依从性良好、安全有效的药物治疗是关键[5]。为了进一步探讨小儿缺铁性贫血采取富马酸亚铁单独治疗与联合健脾生血颗粒治疗的疗效，本院将收治的66例患儿进行了如下研究，现报道如下。
1 资料与方法
1.1 一般资料 选择本院2015年1月-2017年6月收治的小儿缺铁性贫血患儿66例进行研究，纳入标准：确诊符合缺铁性贫血诊断标准[6]；近期无铁剂应用史；家长愿意配合研究，且签署知情同意书。排除标准：近1个月内应用铁剂；严重心肝肾等脏器病变；2周内有腹泻或慢性感染等。按照治疗方案不同分为两组，对照组32例单用富马酸亚铁治疗，治疗组34例采取富马酸亚铁与健脾生血颗粒联合治疗。, http://www.100md.com(肖贞 吴卫照)