不同胰岛素方案治疗妊娠期糖尿病的效果评价(1)
【摘要】 目的：評价与分析不同胰岛素方案治疗妊娠期糖尿病(Gestational diabetes mellitus，GDM)的临床效果。方法：选取本院2016年1月-2017年8月收治的妊娠期糖尿病患者100例为研究对象，根据治疗方案的不同将其分为对照组和观察组，每组50例。观察组采用胰岛素泵持续输注治疗，对照组采用胰岛素分次皮下注射治疗。观察对比两组治疗前后的血糖控制水平以及剖宫产率、母体并发症发生情况。结果：治疗前，两组的糖化血红蛋白(HbA1c)、空腹血糖(FBG)、餐后2 h血糖(2 h PG)水平比较，差异均无统计学意义(P>0.05)；治疗后，观察组的HbA1c、FBG、2 h PG水平与对照组比较均明显改善，差异均有统计学意义(P<0.05)。观察组剖宫产率为8.0%(4/50)，低于对照组的22.0%(11/50)，差异有统计学意义(P<0.05)。观察组母体并发症发生率为10.0%(5/50)，低于对照组的34.0%(17/50)，差异有统计学意义(P<0.05)。结论：采用胰岛素泵持续输注治疗妊娠期糖尿病效果显著，既能有效控制患者血糖水平，又能降低剖宫产率，并能减少各种母体并发症，因此值得应用推广。
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【关键词】 妊娠期糖尿病； 胰岛素
Evaluation of Effect of Different Insulin Regimens in the Treatment of Gestational Diabetes Mellitus/SHEN Yingji.//Medical Innovation of China，2018，15(03)：098-100
【Abstract】 Objective：To evaluate and analyze the clinical efficacy of different insulin regimens in the treatment of gestational diabetes mellitus(GDM).Method：100 patients with gestational diabetes in our hospital from January 2016 to August 2017 were selected as the study objects，according to the different treatment options，they were divided into the control group and observation group，50 cases in each group.The observation group was treated with insulin pump continuous infusion，the control group adopted by several times with subcutaneous insulin injections.The blood glucose control level before and after treatment，cesarean section rate and maternal complications were observed and compared between the two groups.Result：Before treatment，there were no significant differences in the levels of HbA1c，FBG and 2 h PG between the two groups(P>0.05)；after treatment，the levels of HbA1c，FBG，2 h PG were significantly improved in the observation group，compared with the control group，the differences were statistically significant(P<0.05).The rate of cesarean section in the observation group was 8.0%(4/50)，which was significantly lower than 22.0%(11/50) in the control group(P<0.05).The incidence of maternal complications in the observation group was 10.0%(5/50)，which was lower than 34.0%(17/50) of the control group，the difference was statistically significant(P<0.05).Conclusion：Continuous infusion of insulin pump is effective in the treatment of gestational diabetes mellitus，it can not only effectively control blood glucose level，but also reduce the rate of cesarean section，and reduce various maternal complications，so it is worthy of application and promotion.
【Key words】 Gestational diabetes mellitus； Insulin
First-author’s address：Dalian Municipal Women and Children’s Medical Center，Dalian 116037，China, 百拇医药(申英姬)
, http://www.100md.com
【关键词】 妊娠期糖尿病； 胰岛素
Evaluation of Effect of Different Insulin Regimens in the Treatment of Gestational Diabetes Mellitus/SHEN Yingji.//Medical Innovation of China，2018，15(03)：098-100
【Abstract】 Objective：To evaluate and analyze the clinical efficacy of different insulin regimens in the treatment of gestational diabetes mellitus(GDM).Method：100 patients with gestational diabetes in our hospital from January 2016 to August 2017 were selected as the study objects，according to the different treatment options，they were divided into the control group and observation group，50 cases in each group.The observation group was treated with insulin pump continuous infusion，the control group adopted by several times with subcutaneous insulin injections.The blood glucose control level before and after treatment，cesarean section rate and maternal complications were observed and compared between the two groups.Result：Before treatment，there were no significant differences in the levels of HbA1c，FBG and 2 h PG between the two groups(P>0.05)；after treatment，the levels of HbA1c，FBG，2 h PG were significantly improved in the observation group，compared with the control group，the differences were statistically significant(P<0.05).The rate of cesarean section in the observation group was 8.0%(4/50)，which was significantly lower than 22.0%(11/50) in the control group(P<0.05).The incidence of maternal complications in the observation group was 10.0%(5/50)，which was lower than 34.0%(17/50) of the control group，the difference was statistically significant(P<0.05).Conclusion：Continuous infusion of insulin pump is effective in the treatment of gestational diabetes mellitus，it can not only effectively control blood glucose level，but also reduce the rate of cesarean section，and reduce various maternal complications，so it is worthy of application and promotion.
【Key words】 Gestational diabetes mellitus； Insulin
First-author’s address：Dalian Municipal Women and Children’s Medical Center，Dalian 116037，China, 百拇医药(申英姬)
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