用灯盏花素注射液治疗冠心病所致不稳定型心绞痛的效果分析(1)
【摘要】 目的：分析燈盏花素注射液治疗冠心病所致不稳定型心绞痛的临床效果。方法：选取本院2015年6月-2017年7月收治的冠心病所致不稳定型心绞痛患者60例，按随机数字表法分为观察组与对照组，每组各30例。对照组给予常规西药治疗，观察组在对照组基础上加用灯盏花素注射液。比较两组治疗效果，比较两组治疗前后血液流变学参数(全血高切黏度、血浆黏度、红细胞聚集指数、红细胞变形指数)及ADP和COL诱导的血小板聚集率。结果：治疗后，观察组全血高切黏度、血浆黏度值、红细胞聚集指数、红细胞变形指数均低于治疗前和对照组，比较差异均有统计学意义(P<0.05)；治疗后，两组COL、ADP诱导的血小板聚集率均低于治疗前，且观察组均低于对照组，比较差异均有统计学意义(P<0.05)；观察组总有效率为93.33%，明显高于对照组的73.33%，比较差异有统计学意义( 字2=4.320 0，P=0.037 7)。结论：针对冠心病所致不稳定型心绞痛患者，给予灯盏花素注射液治疗具有满意的效果，能够显著改善患者的凝血指标，促进康复，具有较高的推广价值。
, http://www.100md.com 【关键词】 灯盏花素注射液； 冠心病； 不稳定型心绞痛
【Abstract】 Objective：To analyze the clinical effect of Breviscapine Injection in the treatment of unstable angina pectoris caused by coronary heart disease.Method：A total of 60 patients with unstable angina pectoris caused by coronary heart disease were treated in our hospital from June 2015 to July 2017 were selected，according to the random number table method，they were divided into observation group and control group，30 cases in each group.The control group was treated with conventional western medicine，and observation group was treated with Breviscapine Injection on the basis of control group.The treatment effects of two groups was compared，the hemorheological parameters(whole blood viscosity，plasma viscosity，erythrocyte aggregation index，red cell deformation index) and ADP and COL induced platelet aggregation rate before and after treatment between two groups were compared.Result：After treatment，the whole blood viscosity，plasma viscosity，erythrocyte aggregation index and red cell deformation index in observation group were lower than those of before treatment and control group，the differences were statistically significant(P<0.05).After treatment，the ADP and COL induced platelet aggregation rate in two groups were all lower than those of before treatment，and observation group were lower than those of control group，the differences were statistically significant(P<0.05).The total effective rate of observation group was 93.33%，which was significantly higher than 73.33% of control group，the difference was statistically significant( 字2=4.320 0，P=0.037 7).Conclusion：For patients with unstable angina pectoris caused by coronary heart disease，Breviscapine Injection has satisfactory effect，which can significantly improve coagulation index and promote rehabilitation，and has high popularization value.
【Key words】 Breviscapine Injection； Coronary heart disease； Unstable angina pectoris
First-author’s address：Jiangmen Second People’s Hospital，Jiangmen 529000，China, 百拇医药(蒋银送 梁贵深 吕惠娟)
, http://www.100md.com 【关键词】 灯盏花素注射液； 冠心病； 不稳定型心绞痛
【Abstract】 Objective：To analyze the clinical effect of Breviscapine Injection in the treatment of unstable angina pectoris caused by coronary heart disease.Method：A total of 60 patients with unstable angina pectoris caused by coronary heart disease were treated in our hospital from June 2015 to July 2017 were selected，according to the random number table method，they were divided into observation group and control group，30 cases in each group.The control group was treated with conventional western medicine，and observation group was treated with Breviscapine Injection on the basis of control group.The treatment effects of two groups was compared，the hemorheological parameters(whole blood viscosity，plasma viscosity，erythrocyte aggregation index，red cell deformation index) and ADP and COL induced platelet aggregation rate before and after treatment between two groups were compared.Result：After treatment，the whole blood viscosity，plasma viscosity，erythrocyte aggregation index and red cell deformation index in observation group were lower than those of before treatment and control group，the differences were statistically significant(P<0.05).After treatment，the ADP and COL induced platelet aggregation rate in two groups were all lower than those of before treatment，and observation group were lower than those of control group，the differences were statistically significant(P<0.05).The total effective rate of observation group was 93.33%，which was significantly higher than 73.33% of control group，the difference was statistically significant( 字2=4.320 0，P=0.037 7).Conclusion：For patients with unstable angina pectoris caused by coronary heart disease，Breviscapine Injection has satisfactory effect，which can significantly improve coagulation index and promote rehabilitation，and has high popularization value.
【Key words】 Breviscapine Injection； Coronary heart disease； Unstable angina pectoris
First-author’s address：Jiangmen Second People’s Hospital，Jiangmen 529000，China, 百拇医药(蒋银送 梁贵深 吕惠娟)
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