TET2蛋白下调5hmC在膀胱癌细胞T739中低表达(4)
[14] Li W W，Liu M.Distribution of 5-hydroxymethylcytosine in different human tissues[J].J Nucleic Acids，2011，2011：870726.
[15] Kong L，Tan L，Lv R，et al.A primary role of TET proteins in establishment and maintenance of De Novo bivalency at CpG islands[J].Nucleic Acids Res，2016，44(18)：8682-8692.
[16] Kraus T F，Globisch D，Wagner M，et al.Low values of 5-hydroxymethylcytosine(5hmC)，the “sixth base”，are associated with anaplasia in human brain tumours[J].International Journal of Cancer，2012，131(7)：1577-1590.
[17] Haffner M C，Chaux A，Meeker AK，et al.Global 5-hydroxymethylcytosine content is significantly reduced in tissue stem/progenitor cell compartments and in human cancers[J].Oncotarget，2011，2(8)：627-637.
[18] Li W，Liu M.Distribution of 5-hydroxymethylcytosine in different human tissues[J].J Nucleic Acids，2011，2011：870726.
[19]謝素红，翁文浩，李智.TET1对肾癌786-O细胞增殖的影响及其相关机制[J].肿瘤，2012，32(12)：962-968.
[20] Feng S，Jacobsen S E，Reik W.Epigenetic reprogramming in plant and animal development[J].Science，2010，330(6004)：622-627.
(收稿日期：2017-11-30) (本文编辑：程旭然), http://www.100md.com(谢梅茂 王忠军 胡映秋)
[15] Kong L，Tan L，Lv R，et al.A primary role of TET proteins in establishment and maintenance of De Novo bivalency at CpG islands[J].Nucleic Acids Res，2016，44(18)：8682-8692.
[16] Kraus T F，Globisch D，Wagner M，et al.Low values of 5-hydroxymethylcytosine(5hmC)，the “sixth base”，are associated with anaplasia in human brain tumours[J].International Journal of Cancer，2012，131(7)：1577-1590.
[17] Haffner M C，Chaux A，Meeker AK，et al.Global 5-hydroxymethylcytosine content is significantly reduced in tissue stem/progenitor cell compartments and in human cancers[J].Oncotarget，2011，2(8)：627-637.
[18] Li W，Liu M.Distribution of 5-hydroxymethylcytosine in different human tissues[J].J Nucleic Acids，2011，2011：870726.
[19]謝素红，翁文浩，李智.TET1对肾癌786-O细胞增殖的影响及其相关机制[J].肿瘤，2012，32(12)：962-968.
[20] Feng S，Jacobsen S E，Reik W.Epigenetic reprogramming in plant and animal development[J].Science，2010，330(6004)：622-627.
(收稿日期：2017-11-30) (本文编辑：程旭然), http://www.100md.com(谢梅茂 王忠军 胡映秋)
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