综上所述，对于Wagner Ⅰ～Ⅱ级的慢性糖尿病足创面，rhGM-GSF能明显的缩短愈合时间及提高愈合率，但rhGM-GSF对于创面愈合的机制仍有待进一步的研究。

    参考文献

    [1] Adibe O O，Amin S R，Hansen E N，et al.An evidence-based clinical protocol for diagnosis of acute appendicitis decreased the use of computed tomography in children[J].J Pediatr Surg，2011，46(1)：192-196.

    [2] Ansurudeen I，Sunkari V G，Grünler J，et al.Carnosine enhances diabetic wound healing in the db/db mouse model of type 2 diabetes[J].Amino Acids ......