DEAR1蛋白在甲状腺乳头状癌中的表达及临床意义(4)
[6] Chen N，Balasenthil S，Reuther J，et al.DEAR1 is a chromosome 1p35 tumor suppressor and master regulator of TGF-β-driven epithelial-mesenchymal transition[J].Cancer Discov，2013，3(10)：1172-1189.
[7] Quintás-Cardama A，Post S M，Solis L M，et al.Loss of the novel tumour suppressor and polarity gene Trim62 (Dear1) synergizes with oncogenic Ras in invasive lung cancer[J].J Pathol，2014，234(1)：108-119.
[8] Quintás-Cardama A，Zhang N，Qiu Y H，et al.Loss of TRIM62 expression is an independent adverse prognostic factor in acute myeloid leukemia[J].Clinical Lymphoma Myeloma & Leukemia，2015，15(2)：115-127.
, 百拇医药
[9] Chen N，Balasenthil S，Reuther J，et al.DEAR1，a novel tumor suppressor that regulates cell polarity and epithelial plasticity[J].Cancer Res，2014，74(20)：5683-5689.
[10] Bongers P J，Kluijfhout W P，Vriens M W，et al.Is our treatment of well-differentiated thyroid cancer too aggressive？Hemithyroidectomy versus total thyroidectomy[J].Ned Tijdschr Geneeskd，2017，161：D1852.
[11] Huang L，Wang X，Huang X，et al.Diagnostic significance of CK19，galectin-3，CD56，TPO and Ki67 expression and BRAF mutation in papillary thyroid carcinoma[J].Oncol Lett，2018，15(4)：4269-4277.
, 百拇医药
[12] Jin L，Chen E，Dong S，et al.BRAF and TERT promoter mutations in the aggressiveness of papillary thyroid carcinoma：a study of 653 patients[J].Oncotarget，2016，7(14)：18346-18355.
[13] Jung S N，Lim H S，Liu L，et al.LAMB3 mediates metastatic tumor behavior in papillary thyroid cancer by regulating c-MET/Akt signals[J].Sci Rep，2018，8(1)：2718.
[14] Rosignolo F，Sponziello M，Durante C，et al.Expression of PAX8 Target Genes in Papillary Thyroid Carcinoma[J].PLoS One，2016，11(6)：e0156658.
, 百拇医药
[15] Guerra A，Zeppa P，Bifulco M，et al.Concomitant BRAF(V600E) mutationand RET/PTC rearrangement is a frequent occurrence in papillary thyroid carcinoma[J].Thyroid，2014，24(2)：254-259.
[16] Cao Z，Conway K L，Heath R J，et al.Ubiquitin Ligase TRIM62 Regulates CARD9-Mediated Anti-fungal Immunity and Intestinal Inflammation[J].Immunity，2015，43(4)：715-726.
[17] Huang J，Guo L.Knockdown of SOX9 Inhibits the Proliferation，Invasion，and EMT in Thyroid Cancer Cells[J].Oncol Res，2017，25(2)：167-176.
, http://www.100md.com
[18] Zhu Z，Chen W，Yin X，et al.WAVE3 Induces EMT and Promotes Migration and Invasion in Intrahepatic Cholangiocarcinoma[J].Dig Dis Sci，2016，61(7)：1950-1960.
[19] Huang F，Xiao H，Sun B L，et al.Characterization of TRIM62 as a RING finger E3 ubiquitin ligase and its subcellular localization[J].Biochem Biophys Res Commun，2013，432(2)：208-213.
[20] David C J，Huang Y H，Chen M，et al.TGF-β Tumor Suppression through a Lethal EMT[J].Cell，2016，164(5)：1015-1030.
(收稿日期：2018-04-08) (本文編辑：张爽), 百拇医药(蒋烈浩 谭卓 殷珂欣 黄煜庆 温庆良 朱欣 葛明华)
[7] Quintás-Cardama A，Post S M，Solis L M，et al.Loss of the novel tumour suppressor and polarity gene Trim62 (Dear1) synergizes with oncogenic Ras in invasive lung cancer[J].J Pathol，2014，234(1)：108-119.
[8] Quintás-Cardama A，Zhang N，Qiu Y H，et al.Loss of TRIM62 expression is an independent adverse prognostic factor in acute myeloid leukemia[J].Clinical Lymphoma Myeloma & Leukemia，2015，15(2)：115-127.
, 百拇医药
[9] Chen N，Balasenthil S，Reuther J，et al.DEAR1，a novel tumor suppressor that regulates cell polarity and epithelial plasticity[J].Cancer Res，2014，74(20)：5683-5689.
[10] Bongers P J，Kluijfhout W P，Vriens M W，et al.Is our treatment of well-differentiated thyroid cancer too aggressive？Hemithyroidectomy versus total thyroidectomy[J].Ned Tijdschr Geneeskd，2017，161：D1852.
[11] Huang L，Wang X，Huang X，et al.Diagnostic significance of CK19，galectin-3，CD56，TPO and Ki67 expression and BRAF mutation in papillary thyroid carcinoma[J].Oncol Lett，2018，15(4)：4269-4277.
, 百拇医药
[12] Jin L，Chen E，Dong S，et al.BRAF and TERT promoter mutations in the aggressiveness of papillary thyroid carcinoma：a study of 653 patients[J].Oncotarget，2016，7(14)：18346-18355.
[13] Jung S N，Lim H S，Liu L，et al.LAMB3 mediates metastatic tumor behavior in papillary thyroid cancer by regulating c-MET/Akt signals[J].Sci Rep，2018，8(1)：2718.
[14] Rosignolo F，Sponziello M，Durante C，et al.Expression of PAX8 Target Genes in Papillary Thyroid Carcinoma[J].PLoS One，2016，11(6)：e0156658.
, 百拇医药
[15] Guerra A，Zeppa P，Bifulco M，et al.Concomitant BRAF(V600E) mutationand RET/PTC rearrangement is a frequent occurrence in papillary thyroid carcinoma[J].Thyroid，2014，24(2)：254-259.
[16] Cao Z，Conway K L，Heath R J，et al.Ubiquitin Ligase TRIM62 Regulates CARD9-Mediated Anti-fungal Immunity and Intestinal Inflammation[J].Immunity，2015，43(4)：715-726.
[17] Huang J，Guo L.Knockdown of SOX9 Inhibits the Proliferation，Invasion，and EMT in Thyroid Cancer Cells[J].Oncol Res，2017，25(2)：167-176.
, http://www.100md.com
[18] Zhu Z，Chen W，Yin X，et al.WAVE3 Induces EMT and Promotes Migration and Invasion in Intrahepatic Cholangiocarcinoma[J].Dig Dis Sci，2016，61(7)：1950-1960.
[19] Huang F，Xiao H，Sun B L，et al.Characterization of TRIM62 as a RING finger E3 ubiquitin ligase and its subcellular localization[J].Biochem Biophys Res Commun，2013，432(2)：208-213.
[20] David C J，Huang Y H，Chen M，et al.TGF-β Tumor Suppression through a Lethal EMT[J].Cell，2016，164(5)：1015-1030.
(收稿日期：2018-04-08) (本文編辑：张爽), 百拇医药(蒋烈浩 谭卓 殷珂欣 黄煜庆 温庆良 朱欣 葛明华)