BIN1基因多态性与中国福建东南部地区阿尔茨海默病患者的关联研究(4)
[15] Holler C J，Davis P R，Beckett T L，et al.Bridging integrator 1(BIN1) protein expression increases in the Alzheimer’s disease brain and correlates with neurofibrillary tangle pathology[J].
J Alzheimers Dis，2014，42(4)：1221-1227.
[16] Kingwell K.Alzheimer disease：BIN1 variant increases risk of Alzheimer disease through tau[J].Nat Rev Neurol，2013，9(4)：184.
[17] Chapuis J，Hansmannel F，Gistelinck M，et al.Increased expression of BIN1 mediates Alzheimer genetic risk by modulating tau pathology[J].Mol Psychiatry，2013，18(11)：1225-1234.
[18] Sottejeau Y，Bretteville A，Cantrelle F X，et al.Tau phosphorylation regulates the interaction between BIN1's SH3 domain and Tau’s proline-rich domain[J].Acta Neuropathol Commun，2015，3(9)：58.
[19] Li H L，Yang P，Liu Z J，et al.Common variants at Bin1 are associated with sporadic Alzheimer’s disease in the Han Chinese population[J].Psychiatr Genet，2015，25(1)：21-25.
[20] Tan M S，Yu J T，Jiang T，et al.Genetic variation in BIN1 gene and Alzheimer’s disease risk in Han Chinese individuals[J].Neurobiol Aging，2014，35(7)：1-8.
[21] Tao Q Q，Chen Y，Liu Z J，et al.Associations between apolipoprotein E genotypes and serum levels of glucose，cholesterol，and triglycerides in a cognitively normal aging Han Chinese population[J].Clin Interv Aging，2014，9(11)：1063-1067.
(收稿日期：2018-08-07) (本文編辑：董悦), http://www.100md.com(刘祺 李剑鹏 毕敏)
J Alzheimers Dis，2014，42(4)：1221-1227.
[16] Kingwell K.Alzheimer disease：BIN1 variant increases risk of Alzheimer disease through tau[J].Nat Rev Neurol，2013，9(4)：184.
[17] Chapuis J，Hansmannel F，Gistelinck M，et al.Increased expression of BIN1 mediates Alzheimer genetic risk by modulating tau pathology[J].Mol Psychiatry，2013，18(11)：1225-1234.
[18] Sottejeau Y，Bretteville A，Cantrelle F X，et al.Tau phosphorylation regulates the interaction between BIN1's SH3 domain and Tau’s proline-rich domain[J].Acta Neuropathol Commun，2015，3(9)：58.
[19] Li H L，Yang P，Liu Z J，et al.Common variants at Bin1 are associated with sporadic Alzheimer’s disease in the Han Chinese population[J].Psychiatr Genet，2015，25(1)：21-25.
[20] Tan M S，Yu J T，Jiang T，et al.Genetic variation in BIN1 gene and Alzheimer’s disease risk in Han Chinese individuals[J].Neurobiol Aging，2014，35(7)：1-8.
[21] Tao Q Q，Chen Y，Liu Z J，et al.Associations between apolipoprotein E genotypes and serum levels of glucose，cholesterol，and triglycerides in a cognitively normal aging Han Chinese population[J].Clin Interv Aging，2014，9(11)：1063-1067.
(收稿日期：2018-08-07) (本文編辑：董悦), http://www.100md.com(刘祺 李剑鹏 毕敏)
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