不同年龄慢性失眠障碍患者睡眠特征分析(1)
【摘要】 目的：探讨不同年龄的慢性失眠障碍患者的主、客观睡眠特征情况，为临床诊治提供参考。方法：选取本院收治的慢性失眠障碍患者298例，按照年龄将其分为青年组(≤44岁)139例、中年组(45～59岁)96例、老年组(60～89岁)63例。三组均进行匹兹堡睡眠质量指数(PSQI)评估及多导睡眠图(PSG)整夜监测，并对相关指标参数进行分析研究。结果：三组PSQI量表评估及PSG整夜监测指标比较，差异均有统计学意义(P<0.05)，且随年龄增长，PSQI评分、TIB、微觉醒指数、N1和N2睡眠时间及睡眠比例、睡眠期AHI、OSA平均时间、睡眠期PLM、鼾声指数均呈升高趋势，REM和N3睡眠时间及睡眠比例、TST、SWS、睡眠效率、睡眠潜伏期、REM各指标均呈下降趋势，上述指标的组间两两比较，差异均有统计学意义(P<0.05)。结论：不同年龄的慢性失眠障碍患者存在不同睡眠特征，年长的患者更多表现出睡眠时间缩短，觉醒增加，浅睡眠多，深睡眠、REM睡眠少，睡眠不良事件发生增多、使用助眠药多等特点，临床应根据年龄特点采取个性化治疗，以更好改善青年人和中老年人的睡眠，从而提高其心身健康状况和生活质量。
【关键词】 慢性失眠障碍 睡眠特征 多导睡眠图 睡眠结构
[Abstract] Objective： To explore the subjective and objective sleep characteristics of chronic insomnia patients of different ages， and to provide reference for clinical diagnosis and treatment. Method： A total of 298 patients with chronic insomnia were selected， according to their ages， they were divided into 139 cases of young group (no more than 44 years old)， 96 cases of middle-aged group (45-59 years old)， 63 cases of old group (60-89 years old). Three groups were assessed by Pittsburgh sleep quality index (PSQI) and monitored by polysomnography (PSG) throughout the night， and the relevant parameters were analyzed. Result： There were statistically significant differences between the three groups in PSQI evaluation and PSG overnight monitoring indexes (P<0.05)， and with the increase of age， PSQI score， TIB， micro awakening index， sleeping time and proportion of N1 and N2， sleep AHI， OSA average time， sleep PLM， snoring index all increased， sleeping time and proportion of N3 and REM， TST， SWS， sleep efficiency， sleep latency， REM all indexes were increased， the differences between the two groups were statistically significant (P<0.05). Conclusion： There are different sleep characteristics in patients with chronic insomnia of different ages. The older patients show more characteristics such as shorter sleep time， more wakefulness， more light sleep， less deep sleep and REM sleep， more adverse sleep events and more sleeping pills. Individualized treatment should be adopted according to the characteristics of age in order to better improve the sleep of young people and middle-aged and old people， so as to improve their mental and physical health and quality of life.
失眠是比較常见的睡眠问题，在现代社会中有慢性化、年轻化倾向。慢性失眠障碍的患病率为6%～30%，国内成年人的患病率为9.2%～11.2%[1]。失眠状况受人群特征、经济、社会文化差异有所不同，不同年龄的失眠患者的睡眠质量有不同特点，存在较大差异[2];老年失眠患病率大约19%[3]，随着年龄的增大，失眠的问题也随着增多，睡眠调节中枢的退化，睡眠稳定性变差，并与各种生活的压力和身体状况有关[4]。本研究通过对298例慢性失眠障碍患者进行研究，分析不同年龄慢性失眠障碍患者的睡眠特征，对慢性失眠障碍的个性化治疗提供重要参考意义。现报道如下。, 百拇医药(黎柱培 何婉婷 郑丽华 甘晓文 黄淑平)
【关键词】 慢性失眠障碍 睡眠特征 多导睡眠图 睡眠结构
[Abstract] Objective： To explore the subjective and objective sleep characteristics of chronic insomnia patients of different ages， and to provide reference for clinical diagnosis and treatment. Method： A total of 298 patients with chronic insomnia were selected， according to their ages， they were divided into 139 cases of young group (no more than 44 years old)， 96 cases of middle-aged group (45-59 years old)， 63 cases of old group (60-89 years old). Three groups were assessed by Pittsburgh sleep quality index (PSQI) and monitored by polysomnography (PSG) throughout the night， and the relevant parameters were analyzed. Result： There were statistically significant differences between the three groups in PSQI evaluation and PSG overnight monitoring indexes (P<0.05)， and with the increase of age， PSQI score， TIB， micro awakening index， sleeping time and proportion of N1 and N2， sleep AHI， OSA average time， sleep PLM， snoring index all increased， sleeping time and proportion of N3 and REM， TST， SWS， sleep efficiency， sleep latency， REM all indexes were increased， the differences between the two groups were statistically significant (P<0.05). Conclusion： There are different sleep characteristics in patients with chronic insomnia of different ages. The older patients show more characteristics such as shorter sleep time， more wakefulness， more light sleep， less deep sleep and REM sleep， more adverse sleep events and more sleeping pills. Individualized treatment should be adopted according to the characteristics of age in order to better improve the sleep of young people and middle-aged and old people， so as to improve their mental and physical health and quality of life.
失眠是比較常见的睡眠问题，在现代社会中有慢性化、年轻化倾向。慢性失眠障碍的患病率为6%～30%，国内成年人的患病率为9.2%～11.2%[1]。失眠状况受人群特征、经济、社会文化差异有所不同，不同年龄的失眠患者的睡眠质量有不同特点，存在较大差异[2];老年失眠患病率大约19%[3]，随着年龄的增大，失眠的问题也随着增多，睡眠调节中枢的退化，睡眠稳定性变差，并与各种生活的压力和身体状况有关[4]。本研究通过对298例慢性失眠障碍患者进行研究，分析不同年龄慢性失眠障碍患者的睡眠特征，对慢性失眠障碍的个性化治疗提供重要参考意义。现报道如下。, 百拇医药(黎柱培 何婉婷 郑丽华 甘晓文 黄淑平)