许阳琼

    【摘要】 目的：探讨孟鲁司特钠联合布地奈德治疗咳嗽变异性哮喘(cough variant asthma，CVA)对患儿血清炎性因子、肺功能指标及免疫功能的影响。方法：选取2018年2月-2020年2月就诊于本院的92例CVA患儿，按随机数字表法分为对照组和观察组，各46例。对照组予以布地奈德治疗，观察组加用孟鲁司特钠治疗。比较两组血清炎性因子水平、肺功能指标、免疫功能及不良反应发生状况。结果：治疗后，观察组IL-6、TNF-α水平均低于对照组，差异均有统计学意义(P0.05)。结论：孟鲁司特钠联合布地奈德可增强CVA治疗效果，降低患者气道炎症水平，加快肺功能恢复，并利于调节机体免疫功能，促进病情稳定，值得广泛应用。

    【关键词】 咳嗽变异性哮喘 孟鲁司特钠 布地奈德 肺功能 炎性因子

    [Abstract] Objective： To investigate the effect of Montelukast Sodium combined with Budesonide on serum inflammatory factors， lung function and immune function in children with cough variant asthma (CVA). Method： A total of 92 children with CVA admitted to our hospital from February 2018 to February 2020 were selected， they were divided into control group and observation group according to random number table method， 46 cases in each group. The control group was treated with Budesonide ......