郑精选 林进光 陈志强 文学 林涛 陈志健

    【摘要】 目的：探討应用强化降脂方案治疗急性脑梗死(acute cerebral infarction，ACI)并高脂血症患者的效果。方法：选取2018年1月-2019年12月本院收治的100例急性脑梗死并高脂血症患者，按照随机数字表法将患者分成对照组和观察组，各50例。对照组行常规剂量阿托伐他汀，观察组行强化降脂方案治疗，给予大剂量阿托伐他汀。比较两组治疗前后血脂指标、NIHSS评分及并发症发生情况。结果：与治疗前比较，两组治疗4周后的TC、TG、LDL-C均降低，而HDL-C均升高(P0.05)。结论：ACI并高脂血症患者应用强化降脂方案能纠正患者血脂异常，改善患者神经功能缺损，并可通过减轻炎症反应而发挥作用，可作为ACI并高脂血症的有效治疗方案。

    【关键词】 急性脑梗死 高脂血症 强化降脂方案 阿托伐他汀 炎症反应

    [Abstract] Objective： To investigate the efficacy of intensive lipid-lowering regimen in the treatment of acute cerebral infarction (ACI) with hyperlipidemia. Method： A total of 100 patients with acute cerebral infarction complicated with hyperlipidemia admitted to our hospital from January 2018 to December 2019 were selected， they were divided into control group and observation group according to random number table method， with 50 patients in each group. The control group received regular dose of Atorvastatin， the observation group was treated with intensive lipid-lowering regimen， high-dose Atorvastatin. Blood lipid indexes ......