肖海凤

    【摘要】 目的：探究頭孢他啶联合左氧氟沙星治疗老年心衰(HF)合并肺部感染的效果及对血清WBC、PCT的影响。方法：选取本院2017年3月-2020年3月收治的HF合并肺部感染的老年患者76例为研究对象。采用随机数字表法将患者分为联合组和对照组，每组38例。对照组采用头孢他啶治疗，联合组在对照组的基础上加用左氧氟沙星治疗。比较两组患者血液指标、心功能指标水平，比较两组病原菌清除情况。结果：治疗后，两组的IL-6、TNF-α、BNP、WBC、PCT水平均显著低于治疗前，且联合组上述指标均显著低于对照组，差异均有统计学意义(P<0.05)。治疗后，两组LVESD、LVEDD、LVDs水平均显著低于治疗前，且联合组上述指标均低于对照组(P<0.05);治疗后，两组LVEF均显著高于治疗前，且联合组高于对照组(P<0.05)。联合组病原菌清除率为70.7%，显著高于对照组的47.4%，差异有统计学意义(P<0.05)。治疗后，联合组的总有效率为92.11%，显著高于对照组的71.05%，差异有统计学意义(P<0.05)。结论：头孢他啶联合左氧氟沙星治疗老年HF合并肺部感染效果较好，不仅可有效地清除病原菌，降低血清中WBC、PCT水平，还能改善患者的肺部感染和心脏功能。

    【关键词】 头孢他啶 左氧氟沙星 HF 肺部感染 WBC PCT

    Effect of Ceftazidime Combined with Levofloxacin in the Treatment of Senile Heart Failure Complicated with Pulmonary Infection and Its Influence on Serum WBC and PCT/XIAO Haifeng. //Medical Innovation of China， 2021， 18(16)： 0-046

    [Abstract] Objective： To explore the effect of Ceftazidime combined with Levofloxacin in the treatment of elderly heart failure (HF) complicated with pulmonary infection and its influence on serum WBC and PCT. Method： A total of 76 elderly patients with HF complicated with pulmonary infection admitted to our hospital from March 2017 to March 2020 were selected as the research subjects. The patients were divided into combined group and control group by random number table method ......