蔡菁菁

    【摘要】 目的：探究肾康注射液对糖尿病肾病患者微炎性反应与肾脏血流的影响。方法：选择2019年10月-2020年9月本院的86例糖尿病肾病患者为研究对象。将患者随机分为对照组和观察组，每组43例。对照组进行常规糖尿病肾病治疗，观察组则在对照组的基础上加用肾康注射液治疗。比较两组治疗前后的血清微炎性反应指标(CRP、TNF-α及IL-1β)及肾脏各级动脉(肾主动脉、肾段动脉及肾叶间动脉)血流指标(Vmax、Vmin、PI、RI)。结果：治疗前，两组的血清微炎性反应指标及肾脏各级动脉血流指标比较，差异均无统计学意义(P>0.05)。治疗2、4周后，观察组的血清微炎性反应指标及肾脏各级动脉PI和RI均显著低于对照组，肾脏各级动脉Vmax及Vmin均显著高于对照组，差异均有统计学意义(P<0.05)。结论：肾康注射液可显著改善糖尿病肾病患者的微炎性反应与肾脏血流状态，因此在糖尿病肾病患者中的应用价值较高。

    【关键词】 肾康注射液 糖尿病肾病 微炎性反应 肾脏血流

    [Abstract] Objective： To investigate the influence of Shenkang Injection for microinflammatory response and renal blood flow of patients with diabetic nephropathy. Method： A total of 86 patients with diabetic nephropathy in our hospital from October 2019 to September 2020 were selected as the research objects. The patients were randomly divided into control group and observation group， 43 cases in each group. The control group was treated with routine diabetic nephropathy and the observation group was treated with Shenkang Injection on the basis of the control group. The serum microinflammatory response indexes (CRP ......