陈鸿敏

    【摘要】 目的：分析纖维支气管镜肺泡灌洗治疗重症肺炎伴呼吸衰竭患者的效果及对炎症因子的影响。方法：选取2018年1月-2020年1月在本院就诊并治疗的106例重症肺炎伴呼吸衰竭的患者为观察对象。按照随机抽签法将其分为研究组(常规治疗+纤维支气管镜肺泡灌洗治疗)和对照组(常规治疗)，每组53例。比较两组临床疗效、治疗前后炎症因子表达水平、肺功能与血气分析指标。结果：研究组治疗总有效率为94.34%，高于对照组的81.13%(P<0.05)。两组治疗前炎症因子表达水平、肺功能与血气分析指标比较，差异均无统计学意义(P>0.05);治疗后，两组炎症因子表达水平、肺功能与血气分析指标较治疗前均显著改善，且研究组炎症因子表达水平与PaCO2均显著低于对照组，肺功能与PaO2、SpO2及OI水平均显著低于对照组(P<0.05)。结论：对于重症肺炎伴呼吸衰竭患者，纤维支气管镜肺泡灌洗治疗的效果较好，可有效改善肺功能及血气分析水平，降低炎症反应，从而改善预后，值得推广。

    【关键词】 纤维支气管镜 肺泡灌洗 重症肺炎 呼吸衰竭 炎症因子

    Effect of Bronchoalveolar Lavage under Fiberoptic Bronchoscopy in the Treatment of Severe Pneumonia Complicated with Respiratory Failure and Its Influence on Inflammatory Factors/CHEN Hongmin. //Medical Innovation of China， 2021， 18(24)： 0-067

    [Abstract] Objective： To analyze the effect of bronchoalveolar lavage under fiberoptic bronchoscopy in the treatment of severe pneumonia complicated with respiratory failure and its influence on inflammatory factors. Method： A total of 106 cases of severe pneumonia complicated with respiratory failure treated in our hospital from January 2018 to January 2020 were selected as the observation objects. According to the random drawing method ......