孙艺洋 彭子熠 赵雨鑫 孔凡博 王慧

    【摘要】 姜黄素是一种脂溶性多酚类化合物，是姜黄发挥药理作用的主要成分，是从姜黄的根茎中提取得来的。目前研究发现，姜黄素具有抗炎、抗肿瘤、抗纤维化、抗氧化应激等药理作用。在临床研究中，抗炎治疗一直是重点。近年来对姜黄素抗炎作用的研究越来越受关注，因其强大的抗炎活性被广泛应用于各种炎症相关性疾病的治疗中，如糖尿病肾病、阿尔茨海默病、类风湿性关节炎、非酒精性脂肪肝、动脉粥样硬化、结肠炎等。本文旨在通过归纳姜黄素抗炎作用，为临床上治疗炎症性疾病提供参考。

    【关键词】 姜黄素 抗炎作用 糖尿病肾病 阿尔茨海默病 类风湿性关节炎

    Research Progress on Anti-inflammatory Effect of Curcumin in Disease Treatment/SUN Yiyang， PENG Ziyi， ZHAO Yuxin， KONG Fanbo， WANG Hui. //Medical Innovation of China， 2021， 18(27)： -184

    [Abstract] Curcumin is a fat-soluble polyphenol compound. It is the main ingredient in turmeric for its pharmacological effects， which is extracted from the root and stem of turmeric. Current studies have found that curcumin has anti-inflammatory， anti-tumor， anti-fibrosis， anti-oxidative stress and other pharmacological effects. In clinical research， anti-inflammatory treatment has always been the focus. In recent years， the research on curcumin’s anti-inflammatory effect has attracted more and more attention. Because of its strong anti-inflammatory activity， curcumin is widely used in the treatment of various inflammatory related diseases ......